Biomarker Signatures of Quality for Engineering Nasal Chondrocyte-Derived Cartilage

Biomarker Signatures of Quality for Engineering Nasal Chondrocyte-Derived Cartilage

The definition of quality controls for cell therapy and engineered product manufacturing processes is critical for safe, effective, and standardized clinical implementation. Using the example context of cartilage grafts engineered from autologous nasal chondrocytes, currently used for articular cart...

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Bibliographic Details
Main Authors: M. Adelaide Asnaghi, Laura Power, Andrea Barbero, Martin Haug, Ruth Köppl, David Wendt, Ivan Martin
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-04-01
Series:Frontiers in Bioengineering and Biotechnology
Subjects:
regenerative medicine
engineered cartilage
perichondrium
identity/purity
potency
quality controls
Online Access:https://www.frontiersin.org/article/10.3389/fbioe.2020.00283/full

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