Prognostic Value of Cranial Ultrasonography in Comparison with Magnetic Resonance Imaging in Children with Cerebral Palsy: a Population-Based Study
The aim of this population-based study was to evaluate the characteristics of cerebral palsy (CP) in relation to the predominant pattern of the Magnetic Resonance Imaging Classification System (MRI CS) that was analogously applied to the neonatal/early infant cranial ultrasound (CUS). The study incl...
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doaj-81f114beec7b4ac39f66d0934bdb8b9e2020-11-25T03:25:27ZengSestre Milosrdnice University hospital, Institute of Clinical Medical Research Acta Clinica Croatica0353-94661333-94512020-01-01592.260269Prognostic Value of Cranial Ultrasonography in Comparison with Magnetic Resonance Imaging in Children with Cerebral Palsy: a Population-Based StudyVlatka Mejaški Bošnjak0Dunja Čokolić Petrović1Andrea Šimić Klarić2Sunčica Martinec3Katarina Bošnjak Nađ4Sanja Delin5Zagreb Children’s Hospital, School of Medicine, University of Zagreb, Zagreb, CroatiaOsijek University Hospital Centre, Department of Pediatrics, Osijek, CroatiaSchool of Medicine, Josip Juraj Strossmayer University of Osijek, Osijek, Croatia; Požega General Hospital, Department of Pediatrics, Požega, CroatiaKrapinske Toplice Special Hospital for Medical Rehabilitation, Krapinske Toplice, CroatiaSpecial Hospital for Developmental Neurology and Rehabilitation, Zagreb, CroatiaZadar General Hospital, Department of Pediatrics, Zadar, Croatia; School of Medicine, Josip Juraj Strossmayer University of Osijek, Osijek, CroatiaThe aim of this population-based study was to evaluate the characteristics of cerebral palsy (CP) in relation to the predominant pattern of the Magnetic Resonance Imaging Classification System (MRI CS) that was analogously applied to the neonatal/early infant cranial ultrasound (CUS). The study included children born during the 2004-2007 period from the Croatian part (C28 RCP-HR ) of the Surveillance of Cerebral Palsy in Europe (SCPE) CP register. Motor functions, accompanying impairments and brain MRI were evaluated in 227 children, 185 of which also had CUS. Concerning CP types, 56% of children had bilateral spastic, 34% unilateral spastic, 9% dyskinetic and 1% ataxic CP type. Gross Motor Function Classification System (GMFCS) revealed that 62.05% had mild (GMFCS I-III ) and 37.85% had severe motor impairment (GMFCS IV-V). CUS showed white matter injury in 60%, gray matter injury in 12%, maldevelopments in 8%, miscellaneous changes in 14%, while 6% were normal; MRI showed significant agreement (κ=0.675, p<0.001). Neuroimaging findings of maldevelopments and predominant gray matter injury were associated with more severe CP, but 7% of children with CP had normal MRI . As we found very good agreement between CUS and MRI findings, CUS is recommended in children at an increased risk of CP if MRI is not available.https://hrcak.srce.hr/file/354054Cerebral palsyCranial ultrasonographyFunctional classificationMagnetic resonance imagingSurveillance of Cerebral Palsy in Europe |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Vlatka Mejaški Bošnjak Dunja Čokolić Petrović Andrea Šimić Klarić Sunčica Martinec Katarina Bošnjak Nađ Sanja Delin |
spellingShingle |
Vlatka Mejaški Bošnjak Dunja Čokolić Petrović Andrea Šimić Klarić Sunčica Martinec Katarina Bošnjak Nađ Sanja Delin Prognostic Value of Cranial Ultrasonography in Comparison with Magnetic Resonance Imaging in Children with Cerebral Palsy: a Population-Based Study Acta Clinica Croatica Cerebral palsy Cranial ultrasonography Functional classification Magnetic resonance imaging Surveillance of Cerebral Palsy in Europe |
author_facet |
Vlatka Mejaški Bošnjak Dunja Čokolić Petrović Andrea Šimić Klarić Sunčica Martinec Katarina Bošnjak Nađ Sanja Delin |
author_sort |
Vlatka Mejaški Bošnjak |
title |
Prognostic Value of Cranial Ultrasonography in Comparison with Magnetic Resonance Imaging in Children with Cerebral Palsy: a Population-Based Study |
title_short |
Prognostic Value of Cranial Ultrasonography in Comparison with Magnetic Resonance Imaging in Children with Cerebral Palsy: a Population-Based Study |
title_full |
Prognostic Value of Cranial Ultrasonography in Comparison with Magnetic Resonance Imaging in Children with Cerebral Palsy: a Population-Based Study |
title_fullStr |
Prognostic Value of Cranial Ultrasonography in Comparison with Magnetic Resonance Imaging in Children with Cerebral Palsy: a Population-Based Study |
title_full_unstemmed |
Prognostic Value of Cranial Ultrasonography in Comparison with Magnetic Resonance Imaging in Children with Cerebral Palsy: a Population-Based Study |
title_sort |
prognostic value of cranial ultrasonography in comparison with magnetic resonance imaging in children with cerebral palsy: a population-based study |
publisher |
Sestre Milosrdnice University hospital, Institute of Clinical Medical Research |
series |
Acta Clinica Croatica |
issn |
0353-9466 1333-9451 |
publishDate |
2020-01-01 |
description |
The aim of this population-based study was to evaluate the characteristics of cerebral palsy (CP) in relation to the predominant pattern of the Magnetic Resonance Imaging Classification System (MRI CS) that was analogously applied to the neonatal/early infant cranial ultrasound (CUS). The study included children born during the 2004-2007 period from the Croatian part (C28 RCP-HR ) of the Surveillance of Cerebral Palsy in Europe (SCPE) CP register. Motor functions, accompanying impairments and brain MRI were evaluated in 227 children, 185 of which also had CUS. Concerning CP types, 56% of children had bilateral spastic, 34% unilateral spastic, 9% dyskinetic and
1% ataxic CP type. Gross Motor Function Classification System (GMFCS) revealed that 62.05% had mild (GMFCS I-III ) and 37.85% had severe motor impairment (GMFCS IV-V). CUS showed white matter injury in 60%, gray matter injury in 12%, maldevelopments in 8%, miscellaneous changes in 14%, while 6% were normal; MRI showed significant agreement (κ=0.675, p<0.001). Neuroimaging findings of maldevelopments and predominant gray matter injury were associated with more severe CP, but 7% of children with CP had normal MRI . As we found very good agreement between CUS and MRI findings, CUS is recommended in children at an increased risk of CP if MRI is not available. |
topic |
Cerebral palsy Cranial ultrasonography Functional classification Magnetic resonance imaging Surveillance of Cerebral Palsy in Europe |
url |
https://hrcak.srce.hr/file/354054 |
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