Time-dependent LPS exposure commands MSC immunoplasticity through TLR4 activation leading to opposite therapeutic outcome in EAE

Time-dependent LPS exposure commands MSC immunoplasticity through TLR4 activation leading to opposite therapeutic outcome in EAE

Abstract Background Mesenchymal stem cells (MSCs) have been recognized for their regenerative and anti-inflammatory capacity which makes them very attractive to cell therapy, especially those ones to treat inflammatory and autoimmune disease. Two different immune-phenotypes have been described for M...

Full description

Bibliographic Details
Main Authors: Mónica Kurte, Ana María Vega-Letter, Patricia Luz-Crawford, Farida Djouad, Danièle Noël, Maroun Khoury, Flavio Carrión
Format: Article
Language:English
Published: BMC 2020-09-01
Series:Stem Cell Research & Therapy
Subjects:
MSCs
TLR4
LPS
Immunosuppression
Cell plasticity
Autoimmune diseases
Online Access:http://link.springer.com/article/10.1186/s13287-020-01840-2

Internet

http://link.springer.com/article/10.1186/s13287-020-01840-2

Similar Items