Effects of Different Comorbidities on Health-Related Quality of Life among Respiratory Patients in Vietnam

Comorbidities are common in respiratory disease patients and have been well-known to impact their quality of life. The objective of this study is to estimate the minimal clinically important difference (MCID) of the health-related quality of life (HRQOL) among respiratory disease patients with diffe...

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Main Authors: Chau Quy Ngo, Phuong Thu Phan, Giap Van Vu, Quyen Le Thi Pham, Long Hoang Nguyen, Giang Thu Vu, Tung Thanh Tran, Huong Lan Thi Nguyen, Bach Xuan Tran, Carl A. Latkin, Cyrus S. H. Ho, Roger C. M. Ho
Format: Article
Language:English
Published: MDPI AG 2019-02-01
Series:Journal of Clinical Medicine
Subjects:
Online Access:https://www.mdpi.com/2077-0383/8/2/214
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spelling doaj-81f7e5ee31dd4916a329c1fa003fea4e2020-11-24T21:59:12ZengMDPI AGJournal of Clinical Medicine2077-03832019-02-018221410.3390/jcm8020214jcm8020214Effects of Different Comorbidities on Health-Related Quality of Life among Respiratory Patients in VietnamChau Quy Ngo0Phuong Thu Phan1Giap Van Vu2Quyen Le Thi Pham3Long Hoang Nguyen4Giang Thu Vu5Tung Thanh Tran6Huong Lan Thi Nguyen7Bach Xuan Tran8Carl A. Latkin9Cyrus S. H. Ho10Roger C. M. Ho11Department of Internal Medicine, Hanoi Medical University, Hanoi 100000, VietnamDepartment of Internal Medicine, Hanoi Medical University, Hanoi 100000, VietnamDepartment of Internal Medicine, Hanoi Medical University, Hanoi 100000, VietnamDepartment of Internal Medicine, Hanoi Medical University, Hanoi 100000, VietnamCenter of Excellence in Behavioral Medicine, Nguyen Tat Thanh University, Ho Chi Minh City 700000, VietnamCenter of Excellence in Evidence-based Medicine, Nguyen Tat Thanh University, Ho Chi Minh City 700000, VietnamCenter of Excellence in Evidence-based Medicine, Nguyen Tat Thanh University, Ho Chi Minh City 700000, VietnamInstitute for Global Health Innovations, Duy Tan University, Da Nang 550000, VietnamInstitute for Preventive Medicine and Public Health, Hanoi Medical University, Hanoi 100000, VietnamJohns Hopkins Bloomberg School of Public Health, Baltimore, MD 21205, USADepartment of Psychological Medicine, National University Hospital, Singapore 119074, SingaporeCenter of Excellence in Behavioral Medicine, Nguyen Tat Thanh University, Ho Chi Minh City 700000, VietnamComorbidities are common in respiratory disease patients and have been well-known to impact their quality of life. The objective of this study is to estimate the minimal clinically important difference (MCID) of the health-related quality of life (HRQOL) among respiratory disease patients with different comorbidities in a Vietnamese tertiary hospital. We performed a cross-sectional study from October to November 2016 at the Respiratory Center of Bach Mai Hospital, Hanoi, with a total of 508 participants. Information about socio-economic characteristics, HRQOL and comorbidities of participants was collected. ANOVA was used to identify MCID between patients with and without specific comorbid conditions. Tobit regression was used to explore the associations between comorbidities and the HRQOL. Results showed that the prevalence of cardiovascular comorbidities was 23.8%, followed by musculoskeletal diseases (12.0%), digestive diseases (11.8%), endocrine diseases (10.0%), kidney diseases (5.1%) and ear, nose, and throat diseases (4.5%). Regarding HRQOL, having a problem in pain/discomfort was observed in 61.0% of participants, followed by anxiety/depression (48.2%). Mean EQ-5D index was 0.66 (SD (Standard Deviation) = 0.31). The significant MCID (<i>p</i> &lt; 0.05) was found between patients with and without cardiovascular diseases, musculoskeletal diseases, kidney diseases, and endocrine diseases. The multivariate regression model showed that only musculoskeletal diseases were found to be related with the marked decrement of EQ-5D index score (Coef. = &#8722;0.13; 95% CI (Confident Interval) = &#8722;0.23; &#8722;0.02). Suffering at least one chronic illness was correlated to the marked decrease of EQ-5D index score (Coef. = &#8722;0.09; 95% CI = &#8722;0.17; &#8722;0.01). These results underline the importance of appropriate pain management as well as the provision of an interprofessional care approach to patients in order to alleviate the burden of comorbidities to their treatment outcomes and HRQOL.https://www.mdpi.com/2077-0383/8/2/214respiratory diseasescomorbidityHRQOLminimally clinically important differenceVietnam
collection DOAJ
language English
format Article
sources DOAJ
author Chau Quy Ngo
Phuong Thu Phan
Giap Van Vu
Quyen Le Thi Pham
Long Hoang Nguyen
Giang Thu Vu
Tung Thanh Tran
Huong Lan Thi Nguyen
Bach Xuan Tran
Carl A. Latkin
Cyrus S. H. Ho
Roger C. M. Ho
spellingShingle Chau Quy Ngo
Phuong Thu Phan
Giap Van Vu
Quyen Le Thi Pham
Long Hoang Nguyen
Giang Thu Vu
Tung Thanh Tran
Huong Lan Thi Nguyen
Bach Xuan Tran
Carl A. Latkin
Cyrus S. H. Ho
Roger C. M. Ho
Effects of Different Comorbidities on Health-Related Quality of Life among Respiratory Patients in Vietnam
Journal of Clinical Medicine
respiratory diseases
comorbidity
HRQOL
minimally clinically important difference
Vietnam
author_facet Chau Quy Ngo
Phuong Thu Phan
Giap Van Vu
Quyen Le Thi Pham
Long Hoang Nguyen
Giang Thu Vu
Tung Thanh Tran
Huong Lan Thi Nguyen
Bach Xuan Tran
Carl A. Latkin
Cyrus S. H. Ho
Roger C. M. Ho
author_sort Chau Quy Ngo
title Effects of Different Comorbidities on Health-Related Quality of Life among Respiratory Patients in Vietnam
title_short Effects of Different Comorbidities on Health-Related Quality of Life among Respiratory Patients in Vietnam
title_full Effects of Different Comorbidities on Health-Related Quality of Life among Respiratory Patients in Vietnam
title_fullStr Effects of Different Comorbidities on Health-Related Quality of Life among Respiratory Patients in Vietnam
title_full_unstemmed Effects of Different Comorbidities on Health-Related Quality of Life among Respiratory Patients in Vietnam
title_sort effects of different comorbidities on health-related quality of life among respiratory patients in vietnam
publisher MDPI AG
series Journal of Clinical Medicine
issn 2077-0383
publishDate 2019-02-01
description Comorbidities are common in respiratory disease patients and have been well-known to impact their quality of life. The objective of this study is to estimate the minimal clinically important difference (MCID) of the health-related quality of life (HRQOL) among respiratory disease patients with different comorbidities in a Vietnamese tertiary hospital. We performed a cross-sectional study from October to November 2016 at the Respiratory Center of Bach Mai Hospital, Hanoi, with a total of 508 participants. Information about socio-economic characteristics, HRQOL and comorbidities of participants was collected. ANOVA was used to identify MCID between patients with and without specific comorbid conditions. Tobit regression was used to explore the associations between comorbidities and the HRQOL. Results showed that the prevalence of cardiovascular comorbidities was 23.8%, followed by musculoskeletal diseases (12.0%), digestive diseases (11.8%), endocrine diseases (10.0%), kidney diseases (5.1%) and ear, nose, and throat diseases (4.5%). Regarding HRQOL, having a problem in pain/discomfort was observed in 61.0% of participants, followed by anxiety/depression (48.2%). Mean EQ-5D index was 0.66 (SD (Standard Deviation) = 0.31). The significant MCID (<i>p</i> &lt; 0.05) was found between patients with and without cardiovascular diseases, musculoskeletal diseases, kidney diseases, and endocrine diseases. The multivariate regression model showed that only musculoskeletal diseases were found to be related with the marked decrement of EQ-5D index score (Coef. = &#8722;0.13; 95% CI (Confident Interval) = &#8722;0.23; &#8722;0.02). Suffering at least one chronic illness was correlated to the marked decrease of EQ-5D index score (Coef. = &#8722;0.09; 95% CI = &#8722;0.17; &#8722;0.01). These results underline the importance of appropriate pain management as well as the provision of an interprofessional care approach to patients in order to alleviate the burden of comorbidities to their treatment outcomes and HRQOL.
topic respiratory diseases
comorbidity
HRQOL
minimally clinically important difference
Vietnam
url https://www.mdpi.com/2077-0383/8/2/214
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