Investigating Prognostic Factors for Assisted Reproductive Technology Outcomes in Qadir-Mother and Child Hospital of Shiraz, Iran
<strong>Background:</strong> Assisted reproductive technology (ART) helps infertility treatment. In this study, the researchers tried to find several prognostic factors for ART success. <strong>Methods:</strong> Data of 189 couples that had undergone ART at Qadir-Mother and C...
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doaj-81fad6d575f7475c952d28ed7b166f5e2020-11-25T02:35:14ZengShiraz University of Medical SciencesWomen’s Health Bulletin2345-51362382-99902018-10-01541510.5812/whb.6505845519Investigating Prognostic Factors for Assisted Reproductive Technology Outcomes in Qadir-Mother and Child Hospital of Shiraz, IranArdeshir Bahmanimehr0Bahia Namavar Jahromi1Najmeh Moein-Vaziri2Thalassemia and Hemophilia Genetic, PND Research Center, Dastgheib Hospital, Shiraz University of Medical Sciences, Shiraz, IranInfertility Research Center, Shiraz University of Medical Sciences, Shiraz, Iran|Department of Obstetrics and Gynecology, School of Medicine, Shiraz University of Medical Sciences, Shiraz, IranIVF Center, Ghadir Mother and Child Hospital, Shiraz University of Medical Sciences, Shiraz, Iran<strong>Background:</strong> Assisted reproductive technology (ART) helps infertility treatment. In this study, the researchers tried to find several prognostic factors for ART success. <strong>Methods:</strong> Data of 189 couples that had undergone ART at Qadir-Mother and Child hospital, were retrospectively explored. Cycles were classified as succeeded/failed and female/male/combined causes. Three classes of ovarian response based on the number of retrieved oocytes were determined. Duration of ovarian stimulation, dosages of gonadotropins, and sperm parameters were evaluated. Chi square, t-test and Pearson correlation were used for the analysis. <strong>Results:</strong> Couples with male factor infertility had a higher success rate. Female age had a negative correlation with follicle count (r = -0.25), retrieved oocytes (r = -0.25), fertilized oocytes (r= -0.2), and clinical pregnancy (r = -0.21). Female age was negatively correlated with AMH, although not significant. The fertilization rate had a reverse correlation with the basal FSH (r = -0.22, P= 0.01) and LH (r= -0.18, P= 0.05). Finally, ART success rate was positively correlated with the number of follicles before (r = 0.18, P = 0.05) and after retrieval (r = 0.15, P = 0.05) and fertilized oocyte (r = 0.23, P = 0.01). <strong>Conclusions:</strong> Female age, the number of mature follicles before retrieval, the number of retrieved oocyte, and fertilized oocytes are predictive factors in ART outcomes.http://womenshealthbulletin.sums.ac.ir/article_45519_b1508f37c5168b30153bd490846f4aea.pdfassisted reproductive technologyinfertilityovarian response |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Ardeshir Bahmanimehr Bahia Namavar Jahromi Najmeh Moein-Vaziri |
spellingShingle |
Ardeshir Bahmanimehr Bahia Namavar Jahromi Najmeh Moein-Vaziri Investigating Prognostic Factors for Assisted Reproductive Technology Outcomes in Qadir-Mother and Child Hospital of Shiraz, Iran Women’s Health Bulletin assisted reproductive technology infertility ovarian response |
author_facet |
Ardeshir Bahmanimehr Bahia Namavar Jahromi Najmeh Moein-Vaziri |
author_sort |
Ardeshir Bahmanimehr |
title |
Investigating Prognostic Factors for Assisted Reproductive Technology Outcomes in Qadir-Mother and Child Hospital of Shiraz, Iran |
title_short |
Investigating Prognostic Factors for Assisted Reproductive Technology Outcomes in Qadir-Mother and Child Hospital of Shiraz, Iran |
title_full |
Investigating Prognostic Factors for Assisted Reproductive Technology Outcomes in Qadir-Mother and Child Hospital of Shiraz, Iran |
title_fullStr |
Investigating Prognostic Factors for Assisted Reproductive Technology Outcomes in Qadir-Mother and Child Hospital of Shiraz, Iran |
title_full_unstemmed |
Investigating Prognostic Factors for Assisted Reproductive Technology Outcomes in Qadir-Mother and Child Hospital of Shiraz, Iran |
title_sort |
investigating prognostic factors for assisted reproductive technology outcomes in qadir-mother and child hospital of shiraz, iran |
publisher |
Shiraz University of Medical Sciences |
series |
Women’s Health Bulletin |
issn |
2345-5136 2382-9990 |
publishDate |
2018-10-01 |
description |
<strong>Background:</strong> Assisted reproductive technology (ART) helps infertility treatment. In this study, the researchers tried to find several prognostic factors for ART success.
<strong>Methods:</strong> Data of 189 couples that had undergone ART at Qadir-Mother and Child hospital, were retrospectively explored. Cycles were classified as succeeded/failed and female/male/combined causes. Three classes of ovarian response based on the number of retrieved oocytes were determined. Duration of ovarian stimulation, dosages of gonadotropins, and sperm parameters were evaluated. Chi square, t-test and Pearson correlation were used for the analysis.
<strong>Results:</strong> Couples with male factor infertility had a higher success rate. Female age had a negative correlation with follicle count (r = -0.25), retrieved oocytes (r = -0.25), fertilized oocytes (r= -0.2), and clinical pregnancy (r = -0.21). Female age was negatively correlated with AMH, although not significant. The fertilization rate had a reverse correlation with the basal FSH (r = -0.22, P= 0.01) and LH (r= -0.18, P= 0.05). Finally, ART success rate was positively correlated with the number of follicles before (r = 0.18, P = 0.05) and after retrieval (r = 0.15, P = 0.05) and fertilized oocyte (r = 0.23, P = 0.01).
<strong>Conclusions:</strong> Female age, the number of mature follicles before retrieval, the number of retrieved oocyte, and fertilized oocytes are predictive factors in ART outcomes. |
topic |
assisted reproductive technology infertility ovarian response |
url |
http://womenshealthbulletin.sums.ac.ir/article_45519_b1508f37c5168b30153bd490846f4aea.pdf |
work_keys_str_mv |
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