Gauge symmetries and structure of proteins

Gauge symmetries and structure of proteins

We discuss the gauge field theory approach to protein structure study, which allows a natural way to introduce collective degrees of freedom and nonlinear topological structures. Local symmetry of proteins and its breaking in the medium is considered, what allows to derive Abelian Higgs model of pro...

Full description

Bibliographic Details
Main Authors: Molochkov Alexander, Begun Alexander, Niemi Antti
Format: Article
Language:English
Published: EDP Sciences 2017-01-01
Series:EPJ Web of Conferences
Online Access:https://doi.org/10.1051/epjconf/201713704004
id doaj-8201c4a1260548f09b3c3751a1f1dabb
record_format Article
spelling doaj-8201c4a1260548f09b3c3751a1f1dabb2021-08-02T04:03:18ZengEDP SciencesEPJ Web of Conferences2100-014X2017-01-011370400410.1051/epjconf/201713704004epjconf_conf2017_04004Gauge symmetries and structure of proteinsMolochkov Alexander0Begun Alexander1Niemi AnttiLaboratory of Physics of Living Matter, Far Eastern Federal UniversityLaboratory of Physics of Living Matter, Far Eastern Federal UniversityWe discuss the gauge field theory approach to protein structure study, which allows a natural way to introduce collective degrees of freedom and nonlinear topological structures. Local symmetry of proteins and its breaking in the medium is considered, what allows to derive Abelian Higgs model of protein backbone, correct folding of which is defined by gauge symmetry breaking due hydrophobic forces. Within this model structure of protein backbone is defined by superposition of one-dimensional topological solitons (kinks), what allows to reproduce the three-dimensional structure of the protein backbone with precision up to 1A and to predict its dynamics.https://doi.org/10.1051/epjconf/201713704004
collection DOAJ
language English
format Article
sources DOAJ
author Molochkov Alexander
Begun Alexander
Niemi Antti
spellingShingle Molochkov Alexander
Begun Alexander
Niemi Antti
Gauge symmetries and structure of proteins
EPJ Web of Conferences
author_facet Molochkov Alexander
Begun Alexander
Niemi Antti
author_sort Molochkov Alexander
title Gauge symmetries and structure of proteins
title_short Gauge symmetries and structure of proteins
title_full Gauge symmetries and structure of proteins
title_fullStr Gauge symmetries and structure of proteins
title_full_unstemmed Gauge symmetries and structure of proteins
title_sort gauge symmetries and structure of proteins
publisher EDP Sciences
series EPJ Web of Conferences
issn 2100-014X
publishDate 2017-01-01
description We discuss the gauge field theory approach to protein structure study, which allows a natural way to introduce collective degrees of freedom and nonlinear topological structures. Local symmetry of proteins and its breaking in the medium is considered, what allows to derive Abelian Higgs model of protein backbone, correct folding of which is defined by gauge symmetry breaking due hydrophobic forces. Within this model structure of protein backbone is defined by superposition of one-dimensional topological solitons (kinks), what allows to reproduce the three-dimensional structure of the protein backbone with precision up to 1A and to predict its dynamics.
url https://doi.org/10.1051/epjconf/201713704004
work_keys_str_mv AT molochkovalexander gaugesymmetriesandstructureofproteins
AT begunalexander gaugesymmetriesandstructureofproteins
AT niemiantti gaugesymmetriesandstructureofproteins
_version_ 1721242822563069952

Similar Items