Two New Lanostane Triterpenoids from the Branches and Leaves of Polyalthia oblique

Two new lanostane triterpenoids, 20-hydroxyeuphorbol-7-one (1) and 15α-hydroxyeuphorbol-7,11-dione (2), together with four known triterpenoids, euphorbol-7-one (3), friedelin (4), stigmast-4-ene-6α-ol-3-one (5), stigmasta-4-en-3,6-dione (6), were isolated from ethanol extract of the branches and le...

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Main Authors:	Liu-Kai Wang, Cai-Juan Zheng, Xiao-Bao Li, Guang-Ying Chen, Chang-Ri Han, Wen-Hao Chen, Xiao-Ping Song
Format:	Article
Language:	English
Published:	MDPI AG 2014-06-01
Series:	Molecules
Subjects:	Polyalthia obliqua triterpenoid antibacterial activity
Online Access:	http://www.mdpi.com/1420-3049/19/6/7621

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spelling	doaj-82076cb86902430bade2c5835bd9a4d12020-11-24T23:00:35ZengMDPI AGMolecules1420-30492014-06-011967621762810.3390/molecules19067621molecules19067621Two New Lanostane Triterpenoids from the Branches and Leaves of Polyalthia obliqueLiu-Kai Wang0Cai-Juan Zheng1Xiao-Bao Li2Guang-Ying Chen3Chang-Ri Han4Wen-Hao Chen5Xiao-Ping Song6Key Laboratory of Tropical Medicinal Plant Chemistry of Ministry of Education, College of Chemistry and Chemical Engineering, Hainan Normal University, Haikou 571158, Hainan, ChinaKey Laboratory of Tropical Medicinal Plant Chemistry of Ministry of Education, College of Chemistry and Chemical Engineering, Hainan Normal University, Haikou 571158, Hainan, ChinaKey Laboratory of Tropical Medicinal Plant Chemistry of Ministry of Education, College of Chemistry and Chemical Engineering, Hainan Normal University, Haikou 571158, Hainan, ChinaKey Laboratory of Tropical Medicinal Plant Chemistry of Ministry of Education, College of Chemistry and Chemical Engineering, Hainan Normal University, Haikou 571158, Hainan, ChinaKey Laboratory of Tropical Medicinal Plant Chemistry of Ministry of Education, College of Chemistry and Chemical Engineering, Hainan Normal University, Haikou 571158, Hainan, ChinaKey Laboratory of Tropical Medicinal Plant Chemistry of Ministry of Education, College of Chemistry and Chemical Engineering, Hainan Normal University, Haikou 571158, Hainan, ChinaKey Laboratory of Tropical Medicinal Plant Chemistry of Ministry of Education, College of Chemistry and Chemical Engineering, Hainan Normal University, Haikou 571158, Hainan, ChinaTwo new lanostane triterpenoids, 20-hydroxyeuphorbol-7-one (1) and 15α-hydroxyeuphorbol-7,11-dione (2), together with four known triterpenoids, euphorbol-7-one (3), friedelin (4), stigmast-4-ene-6α-ol-3-one (5), stigmasta-4-en-3,6-dione (6), were isolated from ethanol extract of the branches and leaves of Polyalthia obliqua. The structures of 1 and 2 were elucidated on the basis of extensive spectroscopic analysis and comparisons with related known compounds. Antibacterial activities of two new compounds and four known compounds were tested.http://www.mdpi.com/1420-3049/19/6/7621Polyalthia obliquatriterpenoidantibacterial activity
collection	DOAJ
language	English
format	Article
sources	DOAJ
author	Liu-Kai Wang Cai-Juan Zheng Xiao-Bao Li Guang-Ying Chen Chang-Ri Han Wen-Hao Chen Xiao-Ping Song
spellingShingle	Liu-Kai Wang Cai-Juan Zheng Xiao-Bao Li Guang-Ying Chen Chang-Ri Han Wen-Hao Chen Xiao-Ping Song Two New Lanostane Triterpenoids from the Branches and Leaves of Polyalthia oblique Molecules Polyalthia obliqua triterpenoid antibacterial activity
author_facet	Liu-Kai Wang Cai-Juan Zheng Xiao-Bao Li Guang-Ying Chen Chang-Ri Han Wen-Hao Chen Xiao-Ping Song
author_sort	Liu-Kai Wang
title	Two New Lanostane Triterpenoids from the Branches and Leaves of Polyalthia oblique
title_short	Two New Lanostane Triterpenoids from the Branches and Leaves of Polyalthia oblique
title_full	Two New Lanostane Triterpenoids from the Branches and Leaves of Polyalthia oblique
title_fullStr	Two New Lanostane Triterpenoids from the Branches and Leaves of Polyalthia oblique
title_full_unstemmed	Two New Lanostane Triterpenoids from the Branches and Leaves of Polyalthia oblique
title_sort	two new lanostane triterpenoids from the branches and leaves of polyalthia oblique
publisher	MDPI AG
series	Molecules
issn	1420-3049
publishDate	2014-06-01
description	Two new lanostane triterpenoids, 20-hydroxyeuphorbol-7-one (1) and 15α-hydroxyeuphorbol-7,11-dione (2), together with four known triterpenoids, euphorbol-7-one (3), friedelin (4), stigmast-4-ene-6α-ol-3-one (5), stigmasta-4-en-3,6-dione (6), were isolated from ethanol extract of the branches and leaves of Polyalthia obliqua. The structures of 1 and 2 were elucidated on the basis of extensive spectroscopic analysis and comparisons with related known compounds. Antibacterial activities of two new compounds and four known compounds were tested.
topic	Polyalthia obliqua triterpenoid antibacterial activity
url	http://www.mdpi.com/1420-3049/19/6/7621
work_keys_str_mv	AT liukaiwang twonewlanostanetriterpenoidsfromthebranchesandleavesofpolyalthiaoblique AT caijuanzheng twonewlanostanetriterpenoidsfromthebranchesandleavesofpolyalthiaoblique AT xiaobaoli twonewlanostanetriterpenoidsfromthebranchesandleavesofpolyalthiaoblique AT guangyingchen twonewlanostanetriterpenoidsfromthebranchesandleavesofpolyalthiaoblique AT changrihan twonewlanostanetriterpenoidsfromthebranchesandleavesofpolyalthiaoblique AT wenhaochen twonewlanostanetriterpenoidsfromthebranchesandleavesofpolyalthiaoblique AT xiaopingsong twonewlanostanetriterpenoidsfromthebranchesandleavesofpolyalthiaoblique
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Two New Lanostane Triterpenoids from the Branches and Leaves of Polyalthia oblique

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