Frontal cortex-like functions of the subthalamic nucleus

The subthalamic nucleus has been considered a motor structure for a long time. Over the last twenty years, anatomical and behavioral data have highlighted the position of the STN within a prefrontal-associative and a limbic loop, suggesting that the STN should play a critical role in frontal functio...

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Bibliographic Details
Main Authors: Christelle eBaunez, Sylvie eLardeux
Format: Article
Language:English
Published: Frontiers Media S.A. 2011-10-01
Series:Frontiers in Systems Neuroscience
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fnsys.2011.00083/full
Description
Summary:The subthalamic nucleus has been considered a motor structure for a long time. Over the last twenty years, anatomical and behavioral data have highlighted the position of the STN within a prefrontal-associative and a limbic loop, suggesting that the STN should play a critical role in frontal functions such as attention, inhibitory control (including impulsive action, compulsivity, impulsive choice) and motivation. Here we will review the work highlighting these functions of STN.
ISSN:1662-5137