Differential Selective Pressures Experienced by the Aurora Kinase Gene Family

Differential Selective Pressures Experienced by the Aurora Kinase Gene Family

Aurora kinases (AKs) are serine/threonine kinases that are essential for cell division. Humans have three AK genes: AKA, AKB, and AKC. AKA is required for centrosome assembly, centrosome separation, and bipolar spindle assembly, and its mutation leads to abnormal spindle morphology. AKB is required...

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Bibliographic Details
Main Authors: Joni M. Seeling, Alexis A. Farmer, Adam Mansfield, Hyuk Cho, Madhusudan Choudhary
Format: Article
Language:English
Published: MDPI AG 2017-12-01
Series:International Journal of Molecular Sciences
Subjects:
aurora kinase
molecular phylogeny
synonymous
nonsynonymous
Online Access:https://www.mdpi.com/1422-0067/19/1/72

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