Evaluation of Waist Circumference Cut-off Values as a Marker for Fatty Liver among Japanese Workers
Objectives: Metabolic syndrome has received attention as a risk factor for cardiovascular disease, with particular importance attached to visceral fat accumulation, which is associated with lifestyle-related diseases and is strongly correlated with waist circumference. In this study, our aim is to p...
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doaj-82467738105a445ea6967ab09c32e7f82020-11-24T20:52:58ZengElsevierSafety and Health at Work2093-79112012-12-013428729310.5491/SHAW.2012.3.4.287Evaluation of Waist Circumference Cut-off Values as a Marker for Fatty Liver among Japanese WorkersNaomi Abe0Sumihisa Honda1Doosub Jahng2Kyushu Institute of Technology, Graduate School of Life Science & Systems Engineering, FukuokaNagasaki University, Graduate School of Biomedical Sciences, Nagasaki, JapanKyushu Institute of Technology, Graduate School of Life Science & Systems Engineering, FukuokaObjectives: Metabolic syndrome has received attention as a risk factor for cardiovascular disease, with particular importance attached to visceral fat accumulation, which is associated with lifestyle-related diseases and is strongly correlated with waist circumference. In this study, our aim is to propose waist circumference cut-off values that can be used as a marker for fatty liver based on a sample of workers receiving health checkups in Japan. Methods: This study was conducted in a total of 21,866 workers who underwent periodic health checkups between January 2007 and December 2007. The mean age of the subjects was 47.4 years for men (standard deviation [SD]: 8.0) and 44.7 years for women (SD: 6.9). Evaluation included abdominal ultrasound and measurement of waist circumference, body mass index, fasting blood glucose, triglycerides, high-density lipoprotein cholesterol, and blood pressure. Results: Based on receiver operating characteristic curve analysis, the optimal waist circumference cut-off values were shown as 85.0 cm (sensitivity 0.72, specificity 0.69) for men and 80.0 cm (sensitivity 0.75, specificity 0.78) for women. Conclusion: Abdominal ultrasound is the most efficient means of diagnosing fatty liver, but this examination seldom occurs because the test is not routinely performed at workers’ health checkups. In people found to have a high risk of fatty liver, recommendations can be made for abdominal ultrasound based on the waist circumference cut-off values obtained in this study. That is, waist circumference can be used in high risk individuals as an effective marker for early detection of fatty liver.http://www.sciencedirect.com/science/article/pii/S2093791112340067Waist circumferenceFatty liverHealth-check examinationUltrasonographyReceiver operating characteristic (ROC) curve analysis |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Naomi Abe Sumihisa Honda Doosub Jahng |
spellingShingle |
Naomi Abe Sumihisa Honda Doosub Jahng Evaluation of Waist Circumference Cut-off Values as a Marker for Fatty Liver among Japanese Workers Safety and Health at Work Waist circumference Fatty liver Health-check examination Ultrasonography Receiver operating characteristic (ROC) curve analysis |
author_facet |
Naomi Abe Sumihisa Honda Doosub Jahng |
author_sort |
Naomi Abe |
title |
Evaluation of Waist Circumference Cut-off Values as a Marker for Fatty Liver among Japanese Workers |
title_short |
Evaluation of Waist Circumference Cut-off Values as a Marker for Fatty Liver among Japanese Workers |
title_full |
Evaluation of Waist Circumference Cut-off Values as a Marker for Fatty Liver among Japanese Workers |
title_fullStr |
Evaluation of Waist Circumference Cut-off Values as a Marker for Fatty Liver among Japanese Workers |
title_full_unstemmed |
Evaluation of Waist Circumference Cut-off Values as a Marker for Fatty Liver among Japanese Workers |
title_sort |
evaluation of waist circumference cut-off values as a marker for fatty liver among japanese workers |
publisher |
Elsevier |
series |
Safety and Health at Work |
issn |
2093-7911 |
publishDate |
2012-12-01 |
description |
Objectives: Metabolic syndrome has received attention as a risk factor for cardiovascular disease, with particular importance attached to visceral fat accumulation, which is associated with lifestyle-related diseases and is strongly correlated with waist circumference. In this study, our aim is to propose waist circumference cut-off values that can be used as a marker for fatty liver based on a sample of workers receiving health checkups in Japan.
Methods: This study was conducted in a total of 21,866 workers who underwent periodic health checkups between January 2007 and December 2007. The mean age of the subjects was 47.4 years for men (standard deviation [SD]: 8.0) and 44.7 years for women (SD: 6.9). Evaluation included abdominal ultrasound and measurement of waist circumference, body mass index, fasting blood glucose, triglycerides, high-density lipoprotein cholesterol, and blood pressure.
Results: Based on receiver operating characteristic curve analysis, the optimal waist circumference cut-off values were shown as 85.0 cm (sensitivity 0.72, specificity 0.69) for men and 80.0 cm (sensitivity 0.75, specificity 0.78) for women.
Conclusion: Abdominal ultrasound is the most efficient means of diagnosing fatty liver, but this examination seldom occurs because the test is not routinely performed at workers’ health checkups. In people found to have a high risk of fatty liver, recommendations can be made for abdominal ultrasound based on the waist circumference cut-off values obtained in this study. That is, waist circumference can be used in high risk individuals as an effective marker for early detection of fatty liver. |
topic |
Waist circumference Fatty liver Health-check examination Ultrasonography Receiver operating characteristic (ROC) curve analysis |
url |
http://www.sciencedirect.com/science/article/pii/S2093791112340067 |
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