A Study to Compare the Analgesic Efficacy of Intrathecal Bupivacaine Alone with Intrathecal Bupivacaine Midazolam Combination in Patients Undergoing Elective Infraumbilical Surgery
Spinal anaesthesia, which is one of the techniques for infraumbilical surgeries, is most commonly criticized for limited duration of postoperative analgesia. Several adjuvants have been tried along with local anesthetic for prolonging the duration of analgesia. In this study, we have observed the ef...
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doaj-82521d8130d04d2096eae15d6179b7892020-11-24T20:52:58ZengHindawi LimitedAnesthesiology Research and Practice1687-69621687-69702013-01-01201310.1155/2013/567134567134A Study to Compare the Analgesic Efficacy of Intrathecal Bupivacaine Alone with Intrathecal Bupivacaine Midazolam Combination in Patients Undergoing Elective Infraumbilical SurgeryAnirban Chattopadhyay0Souvik Maitra1Suvadeep Sen2Sulagna Bhattacharjee3Amitava Layek4Sugata Pal5Kakali Ghosh6Lilavati Hospital & Research Center, Mumbai 400050, IndiaDepartment of Anaesthesiology and Intensive Care, AIIMS, New Delhi 110029, IndiaDepartment of Anaesthesiology and Intensive Care, AIIMS, New Delhi 110029, IndiaDepartment of Anaesthesiology, IPGME&R and SSKM Hospital, Kolkata 700020, IndiaDepartment of Anaesthesiology, IPGME&R and SSKM Hospital, Kolkata 700020, IndiaDepartment of Anaesthesiology, IPGME&R and SSKM Hospital, Kolkata 700020, IndiaDepartment of Cardiac Anaesthesiology, IPGME&R and SSKM Hospital, Kolkata 700020, IndiaSpinal anaesthesia, which is one of the techniques for infraumbilical surgeries, is most commonly criticized for limited duration of postoperative analgesia. Several adjuvants have been tried along with local anesthetic for prolonging the duration of analgesia. In this study, we have observed the effect of midazolam as an adjuvant in patients undergoing infraumbilical surgery. In this prospective, randomized, double blinded, and parallel group and open label study of 90 adult patients aged 18–60 years, of American Society of Anaesthesiologists (ASA) status I and II, scheduled for elective infraumbilical surgery, were randomly allocated in two groups. Each patient in group “B” received hyperbaric bupivacaine 12.5 mg along with 0.4 mL of normal saline in the subarachnoid block, and patients of group “BM” received 12.5 mg hyperbaric bupivacaine along with preservative free midazolam 0.4 mL (2 mg). We found that use of midazolam as adjuvant with the local anesthetic in spinal anaesthesia significantly increases the duration of analgesia (median 320 min versus 220 min) and motor block (median 255 min versus 195 min) but decreases the incidence of postoperative nausea-vomiting (PONV).http://dx.doi.org/10.1155/2013/567134 |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Anirban Chattopadhyay Souvik Maitra Suvadeep Sen Sulagna Bhattacharjee Amitava Layek Sugata Pal Kakali Ghosh |
spellingShingle |
Anirban Chattopadhyay Souvik Maitra Suvadeep Sen Sulagna Bhattacharjee Amitava Layek Sugata Pal Kakali Ghosh A Study to Compare the Analgesic Efficacy of Intrathecal Bupivacaine Alone with Intrathecal Bupivacaine Midazolam Combination in Patients Undergoing Elective Infraumbilical Surgery Anesthesiology Research and Practice |
author_facet |
Anirban Chattopadhyay Souvik Maitra Suvadeep Sen Sulagna Bhattacharjee Amitava Layek Sugata Pal Kakali Ghosh |
author_sort |
Anirban Chattopadhyay |
title |
A Study to Compare the Analgesic Efficacy of Intrathecal Bupivacaine Alone with Intrathecal Bupivacaine Midazolam Combination in Patients Undergoing Elective Infraumbilical Surgery |
title_short |
A Study to Compare the Analgesic Efficacy of Intrathecal Bupivacaine Alone with Intrathecal Bupivacaine Midazolam Combination in Patients Undergoing Elective Infraumbilical Surgery |
title_full |
A Study to Compare the Analgesic Efficacy of Intrathecal Bupivacaine Alone with Intrathecal Bupivacaine Midazolam Combination in Patients Undergoing Elective Infraumbilical Surgery |
title_fullStr |
A Study to Compare the Analgesic Efficacy of Intrathecal Bupivacaine Alone with Intrathecal Bupivacaine Midazolam Combination in Patients Undergoing Elective Infraumbilical Surgery |
title_full_unstemmed |
A Study to Compare the Analgesic Efficacy of Intrathecal Bupivacaine Alone with Intrathecal Bupivacaine Midazolam Combination in Patients Undergoing Elective Infraumbilical Surgery |
title_sort |
study to compare the analgesic efficacy of intrathecal bupivacaine alone with intrathecal bupivacaine midazolam combination in patients undergoing elective infraumbilical surgery |
publisher |
Hindawi Limited |
series |
Anesthesiology Research and Practice |
issn |
1687-6962 1687-6970 |
publishDate |
2013-01-01 |
description |
Spinal anaesthesia, which is one of the techniques for infraumbilical surgeries, is most commonly criticized for limited duration of postoperative analgesia. Several adjuvants have been tried along with local anesthetic for prolonging the duration of analgesia. In this study, we have observed the effect of midazolam as an adjuvant in patients undergoing infraumbilical surgery. In this prospective, randomized, double blinded, and parallel group and open label study of 90 adult patients aged 18–60 years, of American Society of Anaesthesiologists (ASA) status I and II, scheduled for elective infraumbilical surgery, were randomly allocated in two groups. Each patient in group “B” received hyperbaric bupivacaine 12.5 mg along with 0.4 mL of normal saline in the subarachnoid block, and patients of group “BM” received 12.5 mg hyperbaric bupivacaine along with preservative free midazolam 0.4 mL (2 mg). We found that use of midazolam as adjuvant with the local anesthetic in spinal anaesthesia significantly increases the duration of analgesia (median 320 min versus 220 min) and motor block (median 255 min versus 195 min) but decreases the incidence of postoperative nausea-vomiting (PONV). |
url |
http://dx.doi.org/10.1155/2013/567134 |
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