Non-Cell Autonomous Influence of the Astrocyte System x on Hypoglycaemic Neuronal Cell Death

Despite longstanding evidence that hypoglycaemic neuronal injury is mediated by glutamate excitotoxicity, the cellular and molecular mechanisms involved remain incompletely defined. Here, we demonstrate that the excitotoxic neuronal death that follows GD (glucose deprivation) is initiated by glutama...

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Bibliographic Details
Main Authors: Nicole A Jackman, Shannon E Melchior, James A Hewett, Sandra J Hewett
Format: Article
Language:English
Published: SAGE Publishing 2012-01-01
Series:ASN Neuro
Online Access:https://doi.org/10.1042/AN20110030