Analysis of Antigens of Mycobacterium leprae by Interaction to Sera IgG, IgM, and IgA Response to Improve Diagnosis of Leprosy

Analysis of Antigens of Mycobacterium leprae by Interaction to Sera IgG, IgM, and IgA Response to Improve Diagnosis of Leprosy

Till 2010, several countries have declared less than one leprosy patient among population of 10,000 and themselves feeling as eliminated from leprosy cases. However, new leprosy cases are still appearing from all these countries. In this situation one has to be confident to diagnose leprosy. This re...

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Main Authors: Avnish Kumar, Om Parkash, Bhawneshwar K. Girdhar
Format: Article
Language:English
Published: Hindawi Limited 2014-01-01
Series:BioMed Research International
Online Access:http://dx.doi.org/10.1155/2014/283278
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spelling doaj-826db9ee18f84a83bfd6cfaa80c98a342020-11-24T23:16:28ZengHindawi LimitedBioMed Research International2314-61332314-61412014-01-01201410.1155/2014/283278283278Analysis of Antigens of Mycobacterium leprae by Interaction to Sera IgG, IgM, and IgA Response to Improve Diagnosis of LeprosyAvnish Kumar0Om Parkash1Bhawneshwar K. Girdhar2Department of Biotechnology, School of Life Sciences, Dr. Bhim Rao Ambedkar University, Khandari Campus, Agra, Uttar Pradesh 282004, IndiaDepartment of Immunology, National JALMA Institute for Leprosy and Other Mycobacterial Diseases, Tajganj, Agra, Uttar Pradesh 282001, IndiaShanti Manglik Hospital, Fatehabad Road, Agra 282001, IndiaTill 2010, several countries have declared less than one leprosy patient among population of 10,000 and themselves feeling as eliminated from leprosy cases. However, new leprosy cases are still appearing from all these countries. In this situation one has to be confident to diagnose leprosy. This review paper highlighted already explored antigens for diagnosis purposes and finally suggested better combinations of protein antigens of M. leprae versus immunoglobulin as detector antibody to be useful for leprosy diagnosis.http://dx.doi.org/10.1155/2014/283278
collection DOAJ
language English
format Article
sources DOAJ
author Avnish Kumar
Om Parkash
Bhawneshwar K. Girdhar
spellingShingle Avnish Kumar
Om Parkash
Bhawneshwar K. Girdhar
Analysis of Antigens of Mycobacterium leprae by Interaction to Sera IgG, IgM, and IgA Response to Improve Diagnosis of Leprosy
BioMed Research International
author_facet Avnish Kumar
Om Parkash
Bhawneshwar K. Girdhar
author_sort Avnish Kumar
title Analysis of Antigens of Mycobacterium leprae by Interaction to Sera IgG, IgM, and IgA Response to Improve Diagnosis of Leprosy
title_short Analysis of Antigens of Mycobacterium leprae by Interaction to Sera IgG, IgM, and IgA Response to Improve Diagnosis of Leprosy
title_full Analysis of Antigens of Mycobacterium leprae by Interaction to Sera IgG, IgM, and IgA Response to Improve Diagnosis of Leprosy
title_fullStr Analysis of Antigens of Mycobacterium leprae by Interaction to Sera IgG, IgM, and IgA Response to Improve Diagnosis of Leprosy
title_full_unstemmed Analysis of Antigens of Mycobacterium leprae by Interaction to Sera IgG, IgM, and IgA Response to Improve Diagnosis of Leprosy
title_sort analysis of antigens of mycobacterium leprae by interaction to sera igg, igm, and iga response to improve diagnosis of leprosy
publisher Hindawi Limited
series BioMed Research International
issn 2314-6133
2314-6141
publishDate 2014-01-01
description Till 2010, several countries have declared less than one leprosy patient among population of 10,000 and themselves feeling as eliminated from leprosy cases. However, new leprosy cases are still appearing from all these countries. In this situation one has to be confident to diagnose leprosy. This review paper highlighted already explored antigens for diagnosis purposes and finally suggested better combinations of protein antigens of M. leprae versus immunoglobulin as detector antibody to be useful for leprosy diagnosis.
url http://dx.doi.org/10.1155/2014/283278
work_keys_str_mv AT avnishkumar analysisofantigensofmycobacteriumlepraebyinteractiontoseraiggigmandigaresponsetoimprovediagnosisofleprosy
AT omparkash analysisofantigensofmycobacteriumlepraebyinteractiontoseraiggigmandigaresponsetoimprovediagnosisofleprosy
AT bhawneshwarkgirdhar analysisofantigensofmycobacteriumlepraebyinteractiontoseraiggigmandigaresponsetoimprovediagnosisofleprosy
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