Red cell distribution width as a prognostic marker in diabetes; a pilot cross-sectional study
Introduction:Red cell distribution width (RDW) is one of the important factors in anisocytosis which is related to impairment of erythropoiesis and degradation of erythrocytes. Objectives: The aim of this study was to evaluate the use of RDW as a prognostic marker in diabetic patients. Patients an...
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Society of Diabetic Nephropathy Prevention
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doaj-827a39d70a624242bc9ec494b87c92622020-11-25T02:04:57ZengSociety of Diabetic Nephropathy Prevention Journal of Nephropharmacology2345-42022019-01-01813310.15171/npj.2019.03npj-20190101174318Red cell distribution width as a prognostic marker in diabetes; a pilot cross-sectional studySaeed Shirali0Sara Bahadoram1Seyed Mohamad Kazem Nourbakhsh2Mohammad Bahadoram3Ali Asghar Valipour4Fatemeh Javanmardi5Hyperlipidemia Research Center, Department of Laboratory Sciences School of Paramedical Sciences, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, IranDepartment of Pediatrics, Imam Khomeini Hospital Complex, Tehran University of Medical Sciences, Tehran, IranDepartment of Pediatric Hematology and Oncology, School of Medicine, Tehran University of Medical Sciences, Tehran, IranMedical Student Research Committee, Faculty of Medicine, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, IranSchool of Public Health, Abadan School of Medical Sciences, Abadan, IranDivision of Epidemiology and Biostatistics of Department of Ahvaz Jundishapur University of Medical Sciences, Ahvaz, IranIntroduction:Red cell distribution width (RDW) is one of the important factors in anisocytosis which is related to impairment of erythropoiesis and degradation of erythrocytes. Objectives: The aim of this study was to evaluate the use of RDW as a prognostic marker in diabetic patients. Patients and Methods: This cross-sectional study was conducted on 144 individuals who referred to laboratories in Khuzestan. Of all, 69 persons were diabetic patients and 75 were non-diabetic. Results: The mean fasting blood sugar (FBS) and RDW coefficient of variation (RDW-CV), were 85.20 ± 9.12 mg/dL and 13.26 ± 0.69% respectively, in the non-diabetic group, and 238.65 ± 70.54 mg/dL and 13.50 ± 0.74% respectively, in the diabetic group. In this study, a significant difference of mean FBS (P <0.001) and mean RDW (P=0.04) between groups were detected. Conclusion: In our study, a significant relationship between changes in RDW and changes in blood sugar in diabetic patients was detected. Studying RDW in diabetes delineated higher RDW values than in healthy population. Therefore, it can be recommended to apply serum RDW as a prognostic marker for diabetes. However additional studies on this subject are necessaryhttp://jnephropharmacology.com/PDF/npj-8-3.pdfRed cell distribution widthType 2 diabetesHyperglycemia |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Saeed Shirali Sara Bahadoram Seyed Mohamad Kazem Nourbakhsh Mohammad Bahadoram Ali Asghar Valipour Fatemeh Javanmardi |
spellingShingle |
Saeed Shirali Sara Bahadoram Seyed Mohamad Kazem Nourbakhsh Mohammad Bahadoram Ali Asghar Valipour Fatemeh Javanmardi Red cell distribution width as a prognostic marker in diabetes; a pilot cross-sectional study Journal of Nephropharmacology Red cell distribution width Type 2 diabetes Hyperglycemia |
author_facet |
Saeed Shirali Sara Bahadoram Seyed Mohamad Kazem Nourbakhsh Mohammad Bahadoram Ali Asghar Valipour Fatemeh Javanmardi |
author_sort |
Saeed Shirali |
title |
Red cell distribution width as a prognostic marker in
diabetes; a pilot cross-sectional study |
title_short |
Red cell distribution width as a prognostic marker in
diabetes; a pilot cross-sectional study |
title_full |
Red cell distribution width as a prognostic marker in
diabetes; a pilot cross-sectional study |
title_fullStr |
Red cell distribution width as a prognostic marker in
diabetes; a pilot cross-sectional study |
title_full_unstemmed |
Red cell distribution width as a prognostic marker in
diabetes; a pilot cross-sectional study |
title_sort |
red cell distribution width as a prognostic marker in
diabetes; a pilot cross-sectional study |
publisher |
Society of Diabetic Nephropathy Prevention |
series |
Journal of Nephropharmacology |
issn |
2345-4202 |
publishDate |
2019-01-01 |
description |
Introduction:Red cell distribution width (RDW) is one of the important factors in anisocytosis
which is related to impairment of erythropoiesis and degradation of erythrocytes.
Objectives: The aim of this study was to evaluate the use of RDW as a prognostic marker in
diabetic patients.
Patients and Methods: This cross-sectional study was conducted on 144 individuals who
referred to laboratories in Khuzestan. Of all, 69 persons were diabetic patients and 75 were
non-diabetic.
Results: The mean fasting blood sugar (FBS) and RDW coefficient of variation (RDW-CV),
were 85.20 ± 9.12 mg/dL and 13.26 ± 0.69% respectively, in the non-diabetic group, and 238.65
± 70.54 mg/dL and 13.50 ± 0.74% respectively, in the diabetic group. In this study, a significant
difference of mean FBS (P <0.001) and mean RDW (P=0.04) between groups were detected.
Conclusion: In our study, a significant relationship between changes in RDW and changes in
blood sugar in diabetic patients was detected. Studying RDW in diabetes delineated higher
RDW values than in healthy population. Therefore, it can be recommended to apply serum
RDW as a prognostic marker for diabetes. However additional studies on this subject are
necessary |
topic |
Red cell distribution width Type 2 diabetes Hyperglycemia |
url |
http://jnephropharmacology.com/PDF/npj-8-3.pdf |
work_keys_str_mv |
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