2-Hydroxy-4-(3′-oxo-3′H-benzofuran-2′-yliden)but-2-enoic acid biosynthesis from dibenzofuran using lateral dioxygenation in a Pseudomonas putida strain B6-2 (DSM 28064)

2-Hydroxy-4-(3′-oxo-3′H-benzofuran-2′-yliden)but-2-enoic acid biosynthesis from dibenzofuran using lateral dioxygenation in a Pseudomonas putida strain B6-2 (DSM 28064)

Abstract Background Benzofuran and its derivatives contain central pharmacophores and are important structures in medicinal chemistry. Chemical synthesis of benzofuran rings often requires expensive catalysts and stringent operational conditions. Biosynthesis is recognized as a promising way to save...

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Bibliographic Details
Main Authors: Xin Liu, Weiwei Wang, Haiyang Hu, Xinyu Lu, Lige Zhang, Ping Xu, Hongzhi Tang
Format: Article
Language:English
Published: SpringerOpen 2018-05-01
Series:Bioresources and Bioprocessing
Subjects:
Biosynthesize
Pseudomonas putida
Lateral dioxygenation
HOBB
Online Access:http://link.springer.com/article/10.1186/s40643-018-0209-5

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