SPLICE-q: a Python tool for genome-wide quantification of splicing efficiency

SPLICE-q: a Python tool for genome-wide quantification of splicing efficiency

Abstract Background Introns are generally removed from primary transcripts to form mature RNA molecules in a post-transcriptional process called splicing. An efficient splicing of primary transcripts is an essential step in gene expression and its misregulation is related to numerous human diseases....

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Bibliographic Details
Main Authors: Verônica R. de Melo Costa, Julianus Pfeuffer, Annita Louloupi, Ulf A. V. Ørom, Rosario M. Piro
Format: Article
Language:English
Published: BMC 2021-07-01
Series:BMC Bioinformatics
Subjects:
Splicing efficiency
RNA-seq
Co-transcriptional splicing
Splicing dynamics
Online Access:https://doi.org/10.1186/s12859-021-04282-6

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