Proliferation/quiescence: the controversial "aller-retour"
<p>Abstract</p> <p>The vast majority of cells, from prokaryotes up to vertebrate organisms, spend most of their time in quiescence, a state defined as a temporary and reversible absence of proliferation. Establishing the quiescent state while maintaining the capacity to re-enter th...
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doaj-82b20a0174984e47b10ced49a770b5572020-11-24T21:40:18ZengBMCCell Division1747-10282011-05-01611010.1186/1747-1028-6-10Proliferation/quiescence: the controversial "aller-retour"Sagot IsabelleDaignan-Fornier Bertrand<p>Abstract</p> <p>The vast majority of cells, from prokaryotes up to vertebrate organisms, spend most of their time in quiescence, a state defined as a temporary and reversible absence of proliferation. Establishing the quiescent state while maintaining the capacity to re-enter the proliferation cycle are critical for cell survival and must be tightly orchestrated to avoid pathological proliferation. Hence, studying the biology of quiescent cells is an exciting research field. Taking advantage of technical progress in genomic, transcriptomic and metabolomic, the nature of transitions between proliferation and quiescence have been recently re-visited in budding yeast. Together with new findings in cell biology, these studies resuscitate an old demon in the field: the controversial existence of a "quiescence program".</p> http://www.celldiv.com/content/6/1/10 |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Sagot Isabelle Daignan-Fornier Bertrand |
spellingShingle |
Sagot Isabelle Daignan-Fornier Bertrand Proliferation/quiescence: the controversial "aller-retour" Cell Division |
author_facet |
Sagot Isabelle Daignan-Fornier Bertrand |
author_sort |
Sagot Isabelle |
title |
Proliferation/quiescence: the controversial "aller-retour" |
title_short |
Proliferation/quiescence: the controversial "aller-retour" |
title_full |
Proliferation/quiescence: the controversial "aller-retour" |
title_fullStr |
Proliferation/quiescence: the controversial "aller-retour" |
title_full_unstemmed |
Proliferation/quiescence: the controversial "aller-retour" |
title_sort |
proliferation/quiescence: the controversial "aller-retour" |
publisher |
BMC |
series |
Cell Division |
issn |
1747-1028 |
publishDate |
2011-05-01 |
description |
<p>Abstract</p> <p>The vast majority of cells, from prokaryotes up to vertebrate organisms, spend most of their time in quiescence, a state defined as a temporary and reversible absence of proliferation. Establishing the quiescent state while maintaining the capacity to re-enter the proliferation cycle are critical for cell survival and must be tightly orchestrated to avoid pathological proliferation. Hence, studying the biology of quiescent cells is an exciting research field. Taking advantage of technical progress in genomic, transcriptomic and metabolomic, the nature of transitions between proliferation and quiescence have been recently re-visited in budding yeast. Together with new findings in cell biology, these studies resuscitate an old demon in the field: the controversial existence of a "quiescence program".</p> |
url |
http://www.celldiv.com/content/6/1/10 |
work_keys_str_mv |
AT sagotisabelle proliferationquiescencethecontroversialallerretour AT daignanfornierbertrand proliferationquiescencethecontroversialallerretour |
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