In vivo guiding nitrogen-doped carbon nanozyme for tumor catalytic therapy

If decorated with the right surface modifications, nanoparticles can function as Trojan horses, transporting cell death-facilitating compounds to tumor cells. Here, the authors prepare a particle with four enzyme-like activities and show that ferritin can direct nanoparticles to tumor cells.

Bibliographic Details
Main Authors:	Kelong Fan, Juqun Xi, Lei Fan, Peixia Wang, Chunhua Zhu, Yan Tang, Xiangdong Xu, Minmin Liang, Bing Jiang, Xiyun Yan, Lizeng Gao
Format:	Article
Language:	English
Published:	Nature Publishing Group 2018-04-01
Series:	Nature Communications
Online Access:	https://doi.org/10.1038/s41467-018-03903-8

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spelling	doaj-82b58c0fe333492180f6498c837d6df02021-05-11T10:08:46ZengNature Publishing GroupNature Communications2041-17232018-04-019111110.1038/s41467-018-03903-8In vivo guiding nitrogen-doped carbon nanozyme for tumor catalytic therapyKelong Fan0Juqun Xi1Lei Fan2Peixia Wang3Chunhua Zhu4Yan Tang5Xiangdong Xu6Minmin Liang7Bing Jiang8Xiyun Yan9Lizeng Gao10Key Laboratory of Protein and Peptide Pharmaceuticals, CAS-University of Tokyo Joint Laboratory of Structural Virology and Immunology, Institute of Biophysics, Chinese Academy of SciencesDepartment of Pharmacology, School of Medicine, Institute of Translational Medicine, Yangzhou UniversitySchool of Chemistry and Chemical Engineering, Yangzhou UniversityKey Laboratory of Protein and Peptide Pharmaceuticals, CAS-University of Tokyo Joint Laboratory of Structural Virology and Immunology, Institute of Biophysics, Chinese Academy of SciencesDepartment of Pharmacology, School of Medicine, Institute of Translational Medicine, Yangzhou UniversityDepartment of Pharmacology, School of Medicine, Institute of Translational Medicine, Yangzhou UniversitySchool of Chemistry and Chemical Engineering, Yangzhou UniversityKey Laboratory of Protein and Peptide Pharmaceuticals, CAS-University of Tokyo Joint Laboratory of Structural Virology and Immunology, Institute of Biophysics, Chinese Academy of SciencesKey Laboratory of Protein and Peptide Pharmaceuticals, CAS-University of Tokyo Joint Laboratory of Structural Virology and Immunology, Institute of Biophysics, Chinese Academy of SciencesKey Laboratory of Protein and Peptide Pharmaceuticals, CAS-University of Tokyo Joint Laboratory of Structural Virology and Immunology, Institute of Biophysics, Chinese Academy of SciencesDepartment of Pharmacology, School of Medicine, Institute of Translational Medicine, Yangzhou UniversityIf decorated with the right surface modifications, nanoparticles can function as Trojan horses, transporting cell death-facilitating compounds to tumor cells. Here, the authors prepare a particle with four enzyme-like activities and show that ferritin can direct nanoparticles to tumor cells.https://doi.org/10.1038/s41467-018-03903-8
collection	DOAJ
language	English
format	Article
sources	DOAJ
author	Kelong Fan Juqun Xi Lei Fan Peixia Wang Chunhua Zhu Yan Tang Xiangdong Xu Minmin Liang Bing Jiang Xiyun Yan Lizeng Gao
spellingShingle	Kelong Fan Juqun Xi Lei Fan Peixia Wang Chunhua Zhu Yan Tang Xiangdong Xu Minmin Liang Bing Jiang Xiyun Yan Lizeng Gao In vivo guiding nitrogen-doped carbon nanozyme for tumor catalytic therapy Nature Communications
author_facet	Kelong Fan Juqun Xi Lei Fan Peixia Wang Chunhua Zhu Yan Tang Xiangdong Xu Minmin Liang Bing Jiang Xiyun Yan Lizeng Gao
author_sort	Kelong Fan
title	In vivo guiding nitrogen-doped carbon nanozyme for tumor catalytic therapy
title_short	In vivo guiding nitrogen-doped carbon nanozyme for tumor catalytic therapy
title_full	In vivo guiding nitrogen-doped carbon nanozyme for tumor catalytic therapy
title_fullStr	In vivo guiding nitrogen-doped carbon nanozyme for tumor catalytic therapy
title_full_unstemmed	In vivo guiding nitrogen-doped carbon nanozyme for tumor catalytic therapy
title_sort	in vivo guiding nitrogen-doped carbon nanozyme for tumor catalytic therapy
publisher	Nature Publishing Group
series	Nature Communications
issn	2041-1723
publishDate	2018-04-01
description	If decorated with the right surface modifications, nanoparticles can function as Trojan horses, transporting cell death-facilitating compounds to tumor cells. Here, the authors prepare a particle with four enzyme-like activities and show that ferritin can direct nanoparticles to tumor cells.
url	https://doi.org/10.1038/s41467-018-03903-8
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In vivo guiding nitrogen-doped carbon nanozyme for tumor catalytic therapy

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