Human VPS13A is associated with multiple organelles and influences mitochondrial morphology and lipid droplet motility
The VPS13A gene is associated with the neurodegenerative disorder Chorea Acanthocytosis. It is unknown what the consequences are of impaired function of VPS13A at the subcellular level. We demonstrate that VPS13A is a peripheral membrane protein, associated with mitochondria, the endoplasmic reticul...
Main Authors: | Wondwossen M Yeshaw, Marianne van der Zwaag, Francesco Pinto, Liza L Lahaye, Anita IE Faber, Rubén Gómez-Sánchez, Amalia M Dolga, Conor Poland, Anthony P Monaco, Sven CD van IJzendoorn, Nicola A Grzeschik, Antonio Velayos-Baeza, Ody CM Sibon |
---|---|
Format: | Article |
Language: | English |
Published: |
eLife Sciences Publications Ltd
2019-02-01
|
Series: | eLife |
Subjects: | |
Online Access: | https://elifesciences.org/articles/43561 |
Similar Items
-
Drosophila Vps13 Is Required for Protein Homeostasis in the Brain.
by: Jan J Vonk, et al.
Published: (2017-01-01) -
A Role for the VPS Retromer in Brucella Intracellular Replication Revealed by Genomewide siRNA Screening
by: Alain Casanova, et al.
Published: (2019-06-01) -
Physiological Role of Vps34 Phosphatidylinositol 3-Kinase in Mammalian Cells
by: Johnson, Erin Ellen
Published: (2005) -
Characterization of VPS16B, a Novel Protein Involved in Platelet α-granule Biogenesis
by: Urban, Denisa
Published: (2014) -
Characterization of VPS16B, a Novel Protein Involved in Platelet α-granule Biogenesis
by: Urban, Denisa
Published: (2014)