The Connection between the Presence of Melanoma and Changes in Fibre Diffraction Patterns

• Main Authors: Veronica J. James, Nigel Kirby
• Format: Article
• Language: English
• Published: MDPI AG 2010-06-01
• Series: Cancers
• Subjects: melanoma; diagnosis; x-ray diffraction; skin
• Online Access: http://www.mdpi.com/2072-6694/2/2/1155/

An accurate diagnosis of melanomas at an early stage correlates directly with a better prognosis. However the incidence of melanoma is still increasing along with the number of related deaths. Melanoma cells grow extremely fast, with the result that many patients present after metastasis has occurred, too late for effective treatment. This paper describes the changes in the fibre diffraction patterns of skin that indicate the presence of a melanoma. Identification of these changes would provide an alternative early low-cost, reliable diagnostic test which could be conducted on a regular basis in local radiology facilities using rotating anode X-ray generators or as a mass screening test using suitable small angle x-ray beam-lines at synchrotrons.