The use of ovarian cancer cells from patients undergoing surgery to generate primary cultures capable of undergoing functional analysis.
The use of cell lines or animal models has significant disadvantages when dealing with a set of heterogeneous diseases such as epithelial ovarian cancer. This has clinical relevance in that biomarkers developed using cell line or animal models are often not transferable to the clinical setting. In t...
Main Authors: | Rachel L O Donnell, Aiste McCormick, Asima Mukhopadhyay, Laura C Woodhouse, Madeleine Moat, Anna Grundy, Michelle Dixon, Angelika Kaufman, San Soohoo, Ahmed Elattar, Nicola J Curtin, Richard J Edmondson |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2014-01-01
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Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC3948341?pdf=render |
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