Transcriptional profiling of PPARα−/− and CREB3L3−/− livers reveals disparate regulation of hepatoproliferative and metabolic functions of PPARα

Transcriptional profiling of PPARα−/− and CREB3L3−/− livers reveals disparate regulation of hepatoproliferative and metabolic functions of PPARα

Abstract Background Peroxisome Proliferator-Activated receptor α (PPARα) and cAMP-Responsive Element Binding Protein 3-Like 3 (CREB3L3) are transcription factors involved in the regulation of lipid metabolism in the liver. The aim of the present study was to characterize the interrelationship betwee...

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Bibliographic Details
Main Authors: Philip M. M. Ruppert, Jong-Gil Park, Xu Xu, Kyu Yeon Hur, Ann-Hwee Lee, Sander Kersten
Format: Article
Language:English
Published: BMC 2019-03-01
Series:BMC Genomics
Subjects:
Liver
CREB3L3
PPARα
Fasting
Ketogenic diet
Transcriptomics
Online Access:http://link.springer.com/article/10.1186/s12864-019-5563-y

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