GSK-3β, FYN, and DYRK1A: Master Regulators in Neurodegenerative Pathways

GSK-3β, FYN, and DYRK1A: Master Regulators in Neurodegenerative Pathways

Protein kinases (PKs) have been recognized as central nervous system (CNS)-disease-relevant targets due to their master regulatory role in different signal transduction cascades in the neuroscience space. Among them, GSK-3β, FYN, and DYRK1A play a crucial role in the neurodegeneration context, and t...

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Bibliographic Details
Main Authors: Stefania Demuro, Rita M. C. Di Martino, Jose A. Ortega, Andrea Cavalli
Format: Article
Language:English
Published: MDPI AG 2021-08-01
Series:International Journal of Molecular Sciences
Subjects:
protein kinases (PKs)
central nervous system (CNS)
blood-brain barrier (BBB)
tauopathies
PKs modulation
crosstalk
Online Access:https://www.mdpi.com/1422-0067/22/16/9098

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