Prevalence and pathogenicity of binary toxin–positive Clostridium difficile strains that do not produce toxins A and B

Prevalence and pathogenicity of binary toxin–positive Clostridium difficile strains that do not produce toxins A and B

Clostridium difficile causes antibiotic-associated diarrhoea and pseudomembranous colitis. The main virulence factors of C. difficile are the toxins A (TcdA) and B (TcdB). A third toxin, called binary toxin (CDT), can be detected in 17% to 23% of strains, but its role in human disease has not been c...

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Bibliographic Details
Main Authors: C. Eckert, A. Emirian, A. Le Monnier, L. Cathala, H. De Montclos, J. Goret, P. Berger, A. Petit, A. De Chevigny, H. Jean-Pierre, B. Nebbad, S. Camiade, R. Meckenstock, V. Lalande, H. Marchandin, F. Barbut
Format: Article
Language:English
Published: Elsevier 2015-01-01
Series:New Microbes and New Infections
Subjects:
A−B−CDT+ strains
binary toxin
diagnostic
PCR ribotype 033
toxinotype XI
Clostridium difficileI
Online Access:http://www.sciencedirect.com/science/article/pii/S2052297514000055

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http://www.sciencedirect.com/science/article/pii/S2052297514000055

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