mTOR coordinates transcriptional programs and mitochondrial metabolism of activated Treg subsets to protect tissue homeostasis
The authors previously showed that mTOR controls the function of regulatory T cells. Here they show how this mTOR signaling orchestrates homeostasis of Treg-cell subsets and prevents fatal autoimmunity.
Main Authors: | , , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2018-05-01
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Series: | Nature Communications |
Online Access: | https://doi.org/10.1038/s41467-018-04392-5 |
Summary: | The authors previously showed that mTOR controls the function of regulatory T cells. Here they show how this mTOR signaling orchestrates homeostasis of Treg-cell subsets and prevents fatal autoimmunity. |
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ISSN: | 2041-1723 |