Advances in Antibacterial Functionalized Coatings on Mg and Its Alloys for Medical Use—A Review
As a revolutionary implant material, magnesium and its alloys have many exciting performances, such as biodegradability, mechanical compatibility, and excellent biosecurity. However, the rapid and uncontrollable degradation rate of magnesium greatly hampers its clinical use. Many efforts have been t...
Main Authors: | , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
MDPI AG
2020-08-01
|
Series: | Coatings |
Subjects: | |
Online Access: | https://www.mdpi.com/2079-6412/10/9/828 |
id |
doaj-82f0d01eefae4d2da69c841f6341d515 |
---|---|
record_format |
Article |
spelling |
doaj-82f0d01eefae4d2da69c841f6341d5152020-11-25T03:41:10ZengMDPI AGCoatings2079-64122020-08-011082882810.3390/coatings10090828Advances in Antibacterial Functionalized Coatings on Mg and Its Alloys for Medical Use—A ReviewDan Zhang0Ying Liu1Zhaogang Liu2Qiang Wang3School of Stomatology, China Medical University, Liaoning Provincial Key Laboratory of Oral Diseases, Shenyang 110002, ChinaSchool of Stomatology, Jiamusi University, Jiamusi 154007, ChinaSchool of Stomatology, Jiamusi University, Jiamusi 154007, ChinaSchool of Stomatology, China Medical University, Liaoning Provincial Key Laboratory of Oral Diseases, Shenyang 110002, ChinaAs a revolutionary implant material, magnesium and its alloys have many exciting performances, such as biodegradability, mechanical compatibility, and excellent biosecurity. However, the rapid and uncontrollable degradation rate of magnesium greatly hampers its clinical use. Many efforts have been taken to enhance the corrosion resistance of magnesium. However, it must be noted that improving the corrosion resistance of magnesium will lead to the compromise of its antibacterial abilities, which are attribute and proportional to the alkaline pH during its degradation. Providing antibacterial functionalized coating is one of the best methods for balancing the degradation rate and the antibacterial ability of magnesium. Antibacterial functionalized magnesium is especially well-suited for patients with diabetes and infected wounds. Considering the extremely complex biological environment in the human body and the demands of enhancing corrosion resistance, biocompatibility, osteogenesis, and antibacterial ability, composite coatings with combined properties of different materials may be promising. The aim of this review isto collect and compare recent studies on antibacterial functionalized coatings on magnesium and its alloys. The clinical applications of antibacterial functionalized coatings and their material characteristics, antibacterial abilities, in vitro cytocompatibility, and corrosion resistance are also discussed in detail.https://www.mdpi.com/2079-6412/10/9/828antibacterial functionalized coatingmagnesiumcorrosion resistancepolymer-based coatingsHA-based coatings |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Dan Zhang Ying Liu Zhaogang Liu Qiang Wang |
spellingShingle |
Dan Zhang Ying Liu Zhaogang Liu Qiang Wang Advances in Antibacterial Functionalized Coatings on Mg and Its Alloys for Medical Use—A Review Coatings antibacterial functionalized coating magnesium corrosion resistance polymer-based coatings HA-based coatings |
author_facet |
Dan Zhang Ying Liu Zhaogang Liu Qiang Wang |
author_sort |
Dan Zhang |
title |
Advances in Antibacterial Functionalized Coatings on Mg and Its Alloys for Medical Use—A Review |
title_short |
Advances in Antibacterial Functionalized Coatings on Mg and Its Alloys for Medical Use—A Review |
title_full |
Advances in Antibacterial Functionalized Coatings on Mg and Its Alloys for Medical Use—A Review |
title_fullStr |
Advances in Antibacterial Functionalized Coatings on Mg and Its Alloys for Medical Use—A Review |
title_full_unstemmed |
Advances in Antibacterial Functionalized Coatings on Mg and Its Alloys for Medical Use—A Review |
title_sort |
advances in antibacterial functionalized coatings on mg and its alloys for medical use—a review |
publisher |
MDPI AG |
series |
Coatings |
issn |
2079-6412 |
publishDate |
2020-08-01 |
description |
As a revolutionary implant material, magnesium and its alloys have many exciting performances, such as biodegradability, mechanical compatibility, and excellent biosecurity. However, the rapid and uncontrollable degradation rate of magnesium greatly hampers its clinical use. Many efforts have been taken to enhance the corrosion resistance of magnesium. However, it must be noted that improving the corrosion resistance of magnesium will lead to the compromise of its antibacterial abilities, which are attribute and proportional to the alkaline pH during its degradation. Providing antibacterial functionalized coating is one of the best methods for balancing the degradation rate and the antibacterial ability of magnesium. Antibacterial functionalized magnesium is especially well-suited for patients with diabetes and infected wounds. Considering the extremely complex biological environment in the human body and the demands of enhancing corrosion resistance, biocompatibility, osteogenesis, and antibacterial ability, composite coatings with combined properties of different materials may be promising. The aim of this review isto collect and compare recent studies on antibacterial functionalized coatings on magnesium and its alloys. The clinical applications of antibacterial functionalized coatings and their material characteristics, antibacterial abilities, in vitro cytocompatibility, and corrosion resistance are also discussed in detail. |
topic |
antibacterial functionalized coating magnesium corrosion resistance polymer-based coatings HA-based coatings |
url |
https://www.mdpi.com/2079-6412/10/9/828 |
work_keys_str_mv |
AT danzhang advancesinantibacterialfunctionalizedcoatingsonmganditsalloysformedicaluseareview AT yingliu advancesinantibacterialfunctionalizedcoatingsonmganditsalloysformedicaluseareview AT zhaogangliu advancesinantibacterialfunctionalizedcoatingsonmganditsalloysformedicaluseareview AT qiangwang advancesinantibacterialfunctionalizedcoatingsonmganditsalloysformedicaluseareview |
_version_ |
1724531145346908160 |