Sickle Cell Trait Modulates the Proteome and Phosphoproteome of Plasmodium falciparum-Infected Erythrocytes

Sickle Cell Trait Modulates the Proteome and Phosphoproteome of Plasmodium falciparum-Infected Erythrocytes

The high prevalence of sickle cell disease in some human populations likely results from the protection afforded against severe Plasmodium falciparum malaria and death by heterozygous carriage of HbS. P. falciparum remodels the erythrocyte membrane and skeleton, displaying parasite proteins at the e...

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Bibliographic Details
Main Authors: Margaux Chauvet, Cerina Chhuon, Joanna Lipecka, Sébastien Dechavanne, Célia Dechavanne, Murielle Lohezic, Margherita Ortalli, Damien Pineau, Jean-Antoine Ribeil, Sandra Manceau, Caroline Le Van Kim, Adrian J. F. Luty, Florence Migot-Nabias, Slim Azouzi, Ida Chiara Guerrera, Anaïs Merckx
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-03-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
Plasmodium falciparum
hemoglobin S
erythrocyte
membrane phosphorylation
proteomics
Online Access:https://www.frontiersin.org/articles/10.3389/fcimb.2021.637604/full

Internet

https://www.frontiersin.org/articles/10.3389/fcimb.2021.637604/full

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