Cardiac autonomic dysfunction in obese normotensive children and adolescents
OBJECTIVE:To test the hypothesis that obese normotensive children and adolescents present impaired cardiac autonomic control compared to non-obese normotensive ones.METHODS:For this cross-sectional study, 66 children and adolescents were divided into the following groups: Obese (n=31, 12±3 years old...
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Sociedade de Pediatria de São Paulo
2014-06-01
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doaj-8344774d7c234c01825f608101d76ac42020-11-24T21:51:16ZengSociedade de Pediatria de São PauloRevista Paulista de Pediatria1984-04622014-06-0132224424910.1590/0103-0582201432210213S0103-05822014000200244Cardiac autonomic dysfunction in obese normotensive children and adolescentsIsabelle Magalhães G. FreitasJosiane Aparecida MirandaPedro Augusto C. MiraCarla Marcia M. LannaJorge Roberto P. LimaMateus Camaroti LaterzaOBJECTIVE:To test the hypothesis that obese normotensive children and adolescents present impaired cardiac autonomic control compared to non-obese normotensive ones.METHODS:For this cross-sectional study, 66 children and adolescents were divided into the following groups: Obese (n=31, 12±3 years old) and Non-Obese (n=35, 13±3 years old). Obesity was defined as body mass index greater than the 95thpercentile for age and gender. Blood pressure was measured by oscillometric method after 15 minutes of rest in supine position. The heart rate was continuously registered during ten minutes in the supine position with spontaneous breathing. The cardiac autonomic control was assessed by heart rate variability, which was calculated from the five-minute minor variance of the signal. The derivations were the index that indicates the proportion of the number of times in which normal adjacent R-R intervals present differences >50 miliseconds (pNN50), for the time domain, and, for the spectral analysis, low (LF) and high frequency (HF) bands, besides the low and high frequencies ratio (LF/HF). The results were expressed as mean±standard deviation and compared by Student's t-test or Mann-Whitney's U-test.RESULTS: Systolic blood pressure (116±14 versus 114±13mmHg, p=0.693) and diastolic blood pressure (59±8 versus 60±11mmHg, p=0.458) were similar between the Obese and Non-Obese groups. The pNN50 index (29±21 versus 43±23, p=0.015) and HF band (54±20 versus 64±14 normalized units - n.u., p=0.023) were lower in the Obese Group. The LF band (46±20 versus 36±14 n.u., p=0.023) and LF/HF ratio (1.3±1.6 versus 0.7±0.4, p=0.044) were higher in Obese Group.CONCLUSIONS: Obese normotensive children and adolescents present impairment of cardiac autonomic control.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0103-05822014000200244&lng=en&tlng=enobesidadpresión arterialfrecuencia cardiacasistema nervoso autónomoniñoadolescente |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Isabelle Magalhães G. Freitas Josiane Aparecida Miranda Pedro Augusto C. Mira Carla Marcia M. Lanna Jorge Roberto P. Lima Mateus Camaroti Laterza |
spellingShingle |
Isabelle Magalhães G. Freitas Josiane Aparecida Miranda Pedro Augusto C. Mira Carla Marcia M. Lanna Jorge Roberto P. Lima Mateus Camaroti Laterza Cardiac autonomic dysfunction in obese normotensive children and adolescents Revista Paulista de Pediatria obesidad presión arterial frecuencia cardiaca sistema nervoso autónomo niño adolescente |
author_facet |
Isabelle Magalhães G. Freitas Josiane Aparecida Miranda Pedro Augusto C. Mira Carla Marcia M. Lanna Jorge Roberto P. Lima Mateus Camaroti Laterza |
author_sort |
Isabelle Magalhães G. Freitas |
title |
Cardiac autonomic dysfunction in obese normotensive children and adolescents |
title_short |
Cardiac autonomic dysfunction in obese normotensive children and adolescents |
title_full |
Cardiac autonomic dysfunction in obese normotensive children and adolescents |
title_fullStr |
Cardiac autonomic dysfunction in obese normotensive children and adolescents |
title_full_unstemmed |
Cardiac autonomic dysfunction in obese normotensive children and adolescents |
title_sort |
cardiac autonomic dysfunction in obese normotensive children and adolescents |
publisher |
Sociedade de Pediatria de São Paulo |
series |
Revista Paulista de Pediatria |
issn |
1984-0462 |
publishDate |
2014-06-01 |
description |
OBJECTIVE:To test the hypothesis that obese normotensive children and adolescents present impaired cardiac autonomic control compared to non-obese normotensive ones.METHODS:For this cross-sectional study, 66 children and adolescents were divided into the following groups: Obese (n=31, 12±3 years old) and Non-Obese (n=35, 13±3 years old). Obesity was defined as body mass index greater than the 95thpercentile for age and gender. Blood pressure was measured by oscillometric method after 15 minutes of rest in supine position. The heart rate was continuously registered during ten minutes in the supine position with spontaneous breathing. The cardiac autonomic control was assessed by heart rate variability, which was calculated from the five-minute minor variance of the signal. The derivations were the index that indicates the proportion of the number of times in which normal adjacent R-R intervals present differences >50 miliseconds (pNN50), for the time domain, and, for the spectral analysis, low (LF) and high frequency (HF) bands, besides the low and high frequencies ratio (LF/HF). The results were expressed as mean±standard deviation and compared by Student's t-test or Mann-Whitney's U-test.RESULTS: Systolic blood pressure (116±14 versus 114±13mmHg, p=0.693) and diastolic blood pressure (59±8 versus 60±11mmHg, p=0.458) were similar between the Obese and Non-Obese groups. The pNN50 index (29±21 versus 43±23, p=0.015) and HF band (54±20 versus 64±14 normalized units - n.u., p=0.023) were lower in the Obese Group. The LF band (46±20 versus 36±14 n.u., p=0.023) and LF/HF ratio (1.3±1.6 versus 0.7±0.4, p=0.044) were higher in Obese Group.CONCLUSIONS: Obese normotensive children and adolescents present impairment of cardiac autonomic control. |
topic |
obesidad presión arterial frecuencia cardiaca sistema nervoso autónomo niño adolescente |
url |
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0103-05822014000200244&lng=en&tlng=en |
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