Activation of protein kinase C alpha and delta by bile acids: correlation with bile acid structure and diacylglycerol formation

Activation of protein kinase C alpha and delta by bile acids: correlation with bile acid structure and diacylglycerol formation

The feedback repression of cholesterol 7alpha-hydroxylase transcriptional activity and mRNA levels by taurocholate (TCA) occurs via a protein kinase C (PKC)-dependent signal. To determine whether bile acids could activate PKC indirectly via generation of diacylglycerol (DG), their effects on DG leve...

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Bibliographic Details
Main Authors: Y P Rao, R T Stravitz, Z R Vlahcevic, E C Gurley, J J Sando, P B Hylemon
Format: Article
Language:English
Published: Elsevier 1997-12-01
Series:Journal of Lipid Research
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520300298

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