THE COLORECTAL CANCER: EPIDEMIOLOGY AND PHENOTYPE OF PATIENTS OF THE REPUBLIC OF KHAKASSIA

• Main Authors: Olga Vladimirovna Shtygasheva, Elizaveta Sergeevna Ageeva, Natalya Sergeevna Balobina, Diliya Ismagilovna Manasheva
• Format: Article
• Language: English
• Published: Science and Innovation Center Publishing House 2018-03-01
• Series: В мире научных открытий
• Subjects: колоректальный рак; рак прямой кишки; рак ободочной кишки; аденокарцинома; факторы риска; ожирение.
• Online Access: http://journal-s.org/index.php/vmno/article/view/10565
• ISSN: 2072-0831; 2307-9428

Background. The risk colorectal cancer (CRC) increases with the duration of the course inflammatory bowel disease (IBD), the risk polyp malignancy rises with the size of polyp. The examining and monitoring of hyperplastic and adenomatous polyps plays important role in predictive and early diagnosis of CRC. The aim is research the epidemiological features CRC of Khakassia and frequency of stratify factors of disease risk due to data of vital anamnesis is to form a cohort of patients which must be examine at first. Methods. It analyzed of disease, localization, morphology of tumor, five-years of survival, during 2006–2015. The retrospective analysis of disease of stories. The questionnaire on the data of vital anamnesis. Statistical significant between groups of patients was estimated using the conformity criterion (χ2) at р˂0.05. The correlation analysis was using Spearmen criterion at р˂0.05. Results. From 2011–2015 the amount of patients with CRC consisting of dispensary registration increased compared with 2006–2010. The dominant type was adenocarcinoma different study mature which localized in the rectum more than the colon. During 2011–2015 the amount of patients with disease 1–2 studies and five-year survival after the disease is diagnosed are increased. The middle age of patients was 69 (61–77) years. Women, as a group lived longer than men as much as 10 years. The patients with obesity had risk of CRC more in 1.5 times compared with patient’s normal body weight. The men with low physic activity were in 5 times, smoking in 2 times more compared with women. Prevalence of women and type 2 diabetes mellitus was in 4 times, with cholecystectomy in 2.5 times, with concomitant pathology in 3 times, with prolonged anamnesis inflammatory bowel disease in 5 times compared with men in patients with CRC. Conclusion. Increase in morbidity CRC in Republic of Khakassia due to the increase in primary incidence, including at the expense of actively identified patients, increase in patients with a first diagnosis of CRC in 1–2 stages, increased five-year survival of patients.