Network Walking charts transcriptional dynamics of nitrogen signaling by integrating validated and predicted genome-wide interactions
Temporal control of transcriptional networks enables organisms to adapt to changing environment. Here, the authors use a scaled-up cell-based assay to identify direct targets of nitrogen-early responsive transcription factors and validate a network path mediating dynamic nitrogen signaling in Arabid...
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2019-04-01
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Series: | Nature Communications |
Online Access: | https://doi.org/10.1038/s41467-019-09522-1 |
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doaj-8373c4440151476f9e29c51167aed1f32021-05-11T11:48:53ZengNature Publishing GroupNature Communications2041-17232019-04-0110111310.1038/s41467-019-09522-1Network Walking charts transcriptional dynamics of nitrogen signaling by integrating validated and predicted genome-wide interactionsMatthew D. Brooks0Jacopo Cirrone1Angelo V. Pasquino2Jose M. Alvarez3Joseph Swift4Shipra Mittal5Che-Lun Juang6Kranthi Varala7Rodrigo A. Gutiérrez8Gabriel Krouk9Dennis Shasha10Gloria M. Coruzzi11Center for Genomics and Systems Biology, Department of Biology, New York UniversityCourant Institute for Mathematical Sciences, New York UniversityCenter for Genomics and Systems Biology, Department of Biology, New York UniversityCenter for Genomics and Systems Biology, Department of Biology, New York UniversityCenter for Genomics and Systems Biology, Department of Biology, New York UniversityCenter for Genomics and Systems Biology, Department of Biology, New York UniversityCenter for Genomics and Systems Biology, Department of Biology, New York UniversityHorticulture and Landscape Architecture/Center for Plant Biology, Purdue UniversityDepartamento de Genética Molecular y Microbiología, FONDAP Center for Genome Regulation, Millennium Institute for Integrative Biology, Pontificia Universidad Católica de ChileB&PMP, CNRS, INRA, Université de Montpellier, Montpellier SupAgroCourant Institute for Mathematical Sciences, New York UniversityCenter for Genomics and Systems Biology, Department of Biology, New York UniversityTemporal control of transcriptional networks enables organisms to adapt to changing environment. Here, the authors use a scaled-up cell-based assay to identify direct targets of nitrogen-early responsive transcription factors and validate a network path mediating dynamic nitrogen signaling in Arabidopsis.https://doi.org/10.1038/s41467-019-09522-1 |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Matthew D. Brooks Jacopo Cirrone Angelo V. Pasquino Jose M. Alvarez Joseph Swift Shipra Mittal Che-Lun Juang Kranthi Varala Rodrigo A. Gutiérrez Gabriel Krouk Dennis Shasha Gloria M. Coruzzi |
spellingShingle |
Matthew D. Brooks Jacopo Cirrone Angelo V. Pasquino Jose M. Alvarez Joseph Swift Shipra Mittal Che-Lun Juang Kranthi Varala Rodrigo A. Gutiérrez Gabriel Krouk Dennis Shasha Gloria M. Coruzzi Network Walking charts transcriptional dynamics of nitrogen signaling by integrating validated and predicted genome-wide interactions Nature Communications |
author_facet |
Matthew D. Brooks Jacopo Cirrone Angelo V. Pasquino Jose M. Alvarez Joseph Swift Shipra Mittal Che-Lun Juang Kranthi Varala Rodrigo A. Gutiérrez Gabriel Krouk Dennis Shasha Gloria M. Coruzzi |
author_sort |
Matthew D. Brooks |
title |
Network Walking charts transcriptional dynamics of nitrogen signaling by integrating validated and predicted genome-wide interactions |
title_short |
Network Walking charts transcriptional dynamics of nitrogen signaling by integrating validated and predicted genome-wide interactions |
title_full |
Network Walking charts transcriptional dynamics of nitrogen signaling by integrating validated and predicted genome-wide interactions |
title_fullStr |
Network Walking charts transcriptional dynamics of nitrogen signaling by integrating validated and predicted genome-wide interactions |
title_full_unstemmed |
Network Walking charts transcriptional dynamics of nitrogen signaling by integrating validated and predicted genome-wide interactions |
title_sort |
network walking charts transcriptional dynamics of nitrogen signaling by integrating validated and predicted genome-wide interactions |
publisher |
Nature Publishing Group |
series |
Nature Communications |
issn |
2041-1723 |
publishDate |
2019-04-01 |
description |
Temporal control of transcriptional networks enables organisms to adapt to changing environment. Here, the authors use a scaled-up cell-based assay to identify direct targets of nitrogen-early responsive transcription factors and validate a network path mediating dynamic nitrogen signaling in Arabidopsis. |
url |
https://doi.org/10.1038/s41467-019-09522-1 |
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