β2-microglobulin induces depressive- and anxiety-like behaviors in rat.
β2-microglobulin (B2M), the light chain of major histocompatibility complex class I (MHC I) molecules, has been found to impair hippocampal neurogenesis. Based on the crucial role of hippocampal neurogenesis disturbance in the process of depression and anxiety, the aim of the present study is to inv...
Main Authors: | Ping Zhang, Dan Zeng, Yi-Li Yi, Yi-Yun Tang, Wei Zou, Xue-Feng Yang, Chun-Yan Wang, Xiao-Qing Tang |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2018-01-01
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Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC5968416?pdf=render |
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