Orbital Tumor Revealing a Systemic Sarcoidosis

• Main Authors: Samia Hannanachi Sassi, Rim Dhouib, Fatma Kanchal, Raoudha Doghri, Nadia Boujelbene, Hedi Bouguila, Karima Mrad
• Format: Article
• Language: English
• Published: Tehran University of Medical Sciences 2015-03-01
• Series: Acta Medica Iranica
• Subjects: Orbital pseudotumor; Inflammation; Sarcoidosis
• Online Access: https://acta.tums.ac.ir/index.php/acta/article/view/4909

Ocular involvement is seen in approximately 25% of patients with sarcoidosis. Uveitis is the most common ocular manifestation, but sarcoidosis may involve any part of the eye. Orbital manifestations of sarcoidosis are uncommon with few series in the literature. A 65-year-old woman presented with redness of the right eye and painless, unilateral eyelid swelling. Orbital scanning revealed mass infiltrating the soft tissue of the inferior right orbital quadrant. Biopsy results showed nodular, noncaseating granulomas consistent with sarcoidosis. The complete systemic workup revealed systemic manifestations of sarcoidosis at the time of examination with hilar and mediastinal lymphadenopathies noted on CT scan. The orbital surgical treatment was followed by systemic prednisone therapy with good response. Although rare, orbital sarcoidosis must be considered in the evaluation of orbital tumors in elderly patients. A search for systemic findings should be undertaken and appropriate therapy should be instituted.