A small-molecule/cytokine combination enhances hematopoietic stem cell proliferation via inhibition of cell differentiation

A small-molecule/cytokine combination enhances hematopoietic stem cell proliferation via inhibition of cell differentiation

Abstract Background Accumulated evidence supports the potent stimulating effects of multiple small molecules on the expansion of hematopoietic stem cells (HSCs) which are important for the therapy of various hematological disorders. Here, we report a novel, optimized formula, named the SC cocktail,...

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Bibliographic Details
Main Authors: Lan Wang, Xin Guan, Huihui Wang, Bin Shen, Yu Zhang, Zhihua Ren, Yupo Ma, Xinxin Ding, Yongping Jiang
Format: Article
Language:English
Published: BMC 2017-07-01
Series:Stem Cell Research & Therapy
Subjects:
Hematopoietic stem cells
Small molecules
Expansion
Differentiation inhibition
Online Access:http://link.springer.com/article/10.1186/s13287-017-0625-z

Internet

http://link.springer.com/article/10.1186/s13287-017-0625-z

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