Dissipation kinetics and consumer risk assessment of novaluron + lambda-cyhalothrin co-formulation in cabbage
Cabbage, one of the most popular vegetables in the world is infested by several insect-pests and diseases. Novaluron, a chitin synthesis inhibitor and lambda-cyhalothrin, a synthetic pyrethroid group insecticide are used to manage insect-pests on cabbage. The dissipation kinetics and risk assessment...
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Elsevier
2021-01-01
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Series: | Ecotoxicology and Environmental Safety |
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Online Access: | http://www.sciencedirect.com/science/article/pii/S0147651320313312 |
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doaj-83ba1605a1224285b80be46cbf7a0769 |
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Article |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Krishan Kumar Sharma Vandana Tripathy Soudamini Mohapatra Nagapooja Yogendraiah Matadha Abdul Rashid Khan Pathan Badri Narayan Sharma Jatiender Kumar Dubey Sapna Katna Thomas George Amol Tayade Khushbu Sharma Ruchi Gupta Suresh Walia |
spellingShingle |
Krishan Kumar Sharma Vandana Tripathy Soudamini Mohapatra Nagapooja Yogendraiah Matadha Abdul Rashid Khan Pathan Badri Narayan Sharma Jatiender Kumar Dubey Sapna Katna Thomas George Amol Tayade Khushbu Sharma Ruchi Gupta Suresh Walia Dissipation kinetics and consumer risk assessment of novaluron + lambda-cyhalothrin co-formulation in cabbage Ecotoxicology and Environmental Safety Pesticide residue Novaluron Lambda-cyhalothrin Cabbage OECD MRL calculator Consumer risk assessment |
author_facet |
Krishan Kumar Sharma Vandana Tripathy Soudamini Mohapatra Nagapooja Yogendraiah Matadha Abdul Rashid Khan Pathan Badri Narayan Sharma Jatiender Kumar Dubey Sapna Katna Thomas George Amol Tayade Khushbu Sharma Ruchi Gupta Suresh Walia |
author_sort |
Krishan Kumar Sharma |
title |
Dissipation kinetics and consumer risk assessment of novaluron + lambda-cyhalothrin co-formulation in cabbage |
title_short |
Dissipation kinetics and consumer risk assessment of novaluron + lambda-cyhalothrin co-formulation in cabbage |
title_full |
Dissipation kinetics and consumer risk assessment of novaluron + lambda-cyhalothrin co-formulation in cabbage |
title_fullStr |
Dissipation kinetics and consumer risk assessment of novaluron + lambda-cyhalothrin co-formulation in cabbage |
title_full_unstemmed |
Dissipation kinetics and consumer risk assessment of novaluron + lambda-cyhalothrin co-formulation in cabbage |
title_sort |
dissipation kinetics and consumer risk assessment of novaluron + lambda-cyhalothrin co-formulation in cabbage |
publisher |
Elsevier |
series |
Ecotoxicology and Environmental Safety |
issn |
0147-6513 |
publishDate |
2021-01-01 |
description |
Cabbage, one of the most popular vegetables in the world is infested by several insect-pests and diseases. Novaluron, a chitin synthesis inhibitor and lambda-cyhalothrin, a synthetic pyrethroid group insecticide are used to manage insect-pests on cabbage. The dissipation kinetics and risk assessment of combination formulation (novaluron 9.45% + lambda-cyhalothrin 1.9%) with different modes of action has not yet been investigated in cabbage. Multi–location supervised field trials were therefore, conducted in different agro-climatic regions of India for safety evaluation of the combination product. The co-formulation at the recommended (novaluron 750 g a.i. ha−1 + lambda-cyhalothrin 750 g a.i. ha−1) and double the recommended (novaluron 1500 g a.i. ha−1 + lambda-cyhalothrin 1500 g a.i. ha−1) dose was sprayed on the cabbage crop. The samples were extracted and cleaned up using a modified QuEChERS method, and the residues analyzed by GC–ECD and GC–MS. The half-life (t1/2) varied between 1.77 and 2.51 and 2.00–3.38 days for novaluron and 1.36–2.24 and 1.69–3.82 days for lambda-cyhalothrin in cabbage at respective doses. The Food Safety and Standards Authority of India (FSSAI) has set the MRL of 0.7 mg kg−1 for novaluron at PHI of 5 days, and no MRL is set for lambda-cyhalothrin in cabbage. On the basis of OECD MRL calculator, the MRLs of 0.6 and 1.5 mg kg−1 for novaluron and lambda-cyhalothrin, respectively were calculated at the respective doses at PHI of 3 days. Hazard quotient (HQ) <1, theoretical maximum daily intake (TMDI) < acceptable daily intake (ADI) and < maximum permissible intake (MPI), percent acute hazard index (% aHI) <1, and percent chronic hazard index (% cHI) <1 for both novaluron and lambda-cyhalothrin suggested that the combination formulation is safe and will not pose any dietary risk to the consumers. The study will be helpful to conduct risk assessment of other pesticides/combination pesticides on food crops on which their MRLs have not yet been fixed. |
topic |
Pesticide residue Novaluron Lambda-cyhalothrin Cabbage OECD MRL calculator Consumer risk assessment |
url |
http://www.sciencedirect.com/science/article/pii/S0147651320313312 |
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doaj-83ba1605a1224285b80be46cbf7a07692021-04-23T06:14:14ZengElsevierEcotoxicology and Environmental Safety0147-65132021-01-01208111494Dissipation kinetics and consumer risk assessment of novaluron + lambda-cyhalothrin co-formulation in cabbageKrishan Kumar Sharma0Vandana Tripathy1Soudamini Mohapatra2Nagapooja Yogendraiah Matadha3Abdul Rashid Khan Pathan4Badri Narayan Sharma5Jatiender Kumar Dubey6Sapna Katna7Thomas George8Amol Tayade9Khushbu Sharma10Ruchi Gupta11Suresh Walia12Project Coordinating Cell, Pesticide Residue Laboratory, All India Network Project on Pesticide Residues, ICAR–Indian Agricultural Research Institute, New Delhi, India; Corresponding author.Project Coordinating Cell, Pesticide Residue Laboratory, All India Network Project on Pesticide Residues, ICAR–Indian Agricultural Research Institute, New Delhi, IndiaIndian Institute of Horticultural Research (IIHR), All India Network Project on Pesticide Residues, Bangalore, Karnataka, IndiaIndian Institute of Horticultural Research (IIHR), All India Network Project on Pesticide Residues, Bangalore, Karnataka, IndiaSri Karan Narendra Agriculture University (SKNAU), All India Network Project on Pesticide Residues, Durgapura, Jaipur, IndiaSri Karan Narendra Agriculture University (SKNAU), All India Network Project on Pesticide Residues, Durgapura, Jaipur, IndiaDr YS Parmar University of Horticulture and Forestry (Dr YSPUHF), All India Network Project on Pesticide Residues, Solan, Himachal Pradesh, IndiaDr YS Parmar University of Horticulture and Forestry (Dr YSPUHF), All India Network Project on Pesticide Residues, Solan, Himachal Pradesh, IndiaKerala Agricultural University (KAU), All India Network Project on Pesticide Residues, Vellayani, Kerala, IndiaProject Coordinating Cell, Pesticide Residue Laboratory, All India Network Project on Pesticide Residues, ICAR–Indian Agricultural Research Institute, New Delhi, IndiaProject Coordinating Cell, Pesticide Residue Laboratory, All India Network Project on Pesticide Residues, ICAR–Indian Agricultural Research Institute, New Delhi, IndiaProject Coordinating Cell, Pesticide Residue Laboratory, All India Network Project on Pesticide Residues, ICAR–Indian Agricultural Research Institute, New Delhi, IndiaProject Coordinating Cell, Pesticide Residue Laboratory, All India Network Project on Pesticide Residues, ICAR–Indian Agricultural Research Institute, New Delhi, IndiaCabbage, one of the most popular vegetables in the world is infested by several insect-pests and diseases. Novaluron, a chitin synthesis inhibitor and lambda-cyhalothrin, a synthetic pyrethroid group insecticide are used to manage insect-pests on cabbage. The dissipation kinetics and risk assessment of combination formulation (novaluron 9.45% + lambda-cyhalothrin 1.9%) with different modes of action has not yet been investigated in cabbage. Multi–location supervised field trials were therefore, conducted in different agro-climatic regions of India for safety evaluation of the combination product. The co-formulation at the recommended (novaluron 750 g a.i. ha−1 + lambda-cyhalothrin 750 g a.i. ha−1) and double the recommended (novaluron 1500 g a.i. ha−1 + lambda-cyhalothrin 1500 g a.i. ha−1) dose was sprayed on the cabbage crop. The samples were extracted and cleaned up using a modified QuEChERS method, and the residues analyzed by GC–ECD and GC–MS. The half-life (t1/2) varied between 1.77 and 2.51 and 2.00–3.38 days for novaluron and 1.36–2.24 and 1.69–3.82 days for lambda-cyhalothrin in cabbage at respective doses. The Food Safety and Standards Authority of India (FSSAI) has set the MRL of 0.7 mg kg−1 for novaluron at PHI of 5 days, and no MRL is set for lambda-cyhalothrin in cabbage. On the basis of OECD MRL calculator, the MRLs of 0.6 and 1.5 mg kg−1 for novaluron and lambda-cyhalothrin, respectively were calculated at the respective doses at PHI of 3 days. Hazard quotient (HQ) <1, theoretical maximum daily intake (TMDI) < acceptable daily intake (ADI) and < maximum permissible intake (MPI), percent acute hazard index (% aHI) <1, and percent chronic hazard index (% cHI) <1 for both novaluron and lambda-cyhalothrin suggested that the combination formulation is safe and will not pose any dietary risk to the consumers. The study will be helpful to conduct risk assessment of other pesticides/combination pesticides on food crops on which their MRLs have not yet been fixed.http://www.sciencedirect.com/science/article/pii/S0147651320313312Pesticide residueNovaluronLambda-cyhalothrinCabbageOECD MRL calculatorConsumer risk assessment |