Novel tumor suppressor function of glucocorticoid-induced TNF receptor GITR in multiple myeloma.

Novel tumor suppressor function of glucocorticoid-induced TNF receptor GITR in multiple myeloma.

Glucocorticoid-induced TNF receptor (GITR) plays a crucial role in modulating immune response and inflammation, however the role of GITR in human cancers is poorly understood. In this study, we demonstrated that GITR is inactivated during tumor progression in Multiple Myeloma (MM) through promoter C...

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Bibliographic Details
Main Authors: Yang Liu, Phong Quang, Esteban Braggio, Hai Ngo, Gayane Badalian-Very, Ludmila Flores, Yong Zhang, Antonio Sacco, Patricia Maiso, Abdel Kareem Azab, Feda Azab, Ruben Carrasco, Barrett J Rollins, Aldo M Roccaro, Irene M Ghobrial
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3681775?pdf=render

Internet

http://europepmc.org/articles/PMC3681775?pdf=render

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