Virtual screening as a tool to discover new β-haematin inhibitors with activity against malaria parasites
Abstract Malaria remains a major public health problem. With the loss of antimalarials to resistance, the malaria burden will likely continue for decades. New antimalarial scaffolds are crucial to avoid cross-resistance. Here, we present the first structure based virtual screening using the β-haemat...
Main Authors: | Ana Carolina C. de Sousa, Jill M. Combrinck, Keletso Maepa, Timothy J. Egan |
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Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2020-02-01
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Series: | Scientific Reports |
Online Access: | https://doi.org/10.1038/s41598-020-60221-0 |
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