Quality of life in <i>Wilson′s disease</i>
<b>Background:</b> Assessment of Quality of life (QoL) is fast assuming significance as the measure of health in many disorders. <b> Aim:</b> To correlate clinical severity and QoL in patients with Wilson′s disease (WD). <b> Materials and Methods:</b>...
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doaj-8417531a0e07435f81432b42bda37f892020-11-25T02:31:25ZengWolters Kluwer Medknow PublicationsAnnals of Indian Academy of Neurology0972-23271998-35492008-01-011113740Quality of life in <i>Wilson′s disease</i>Komal Kumar RTaly ANair K.P.SSinha SPrashanth LVidya NArunodaya GRao S<b>Background:</b> Assessment of Quality of life (QoL) is fast assuming significance as the measure of health in many disorders. <b> Aim:</b> To correlate clinical severity and QoL in patients with Wilson′s disease (WD). <b> Materials and Methods:</b> We evaluated patients of WD on regular follow up for at least two years and aged over 18 years using Neurological Symptom Score (NSS) for clinical severity and WHO-BREF for QoL at a university teaching hospital. Patients with inability to respond to the questionnaire due to behavioral problems, low IQ or other disease related factors were excluded. These 30 patients (M:F:: 23:7) had a mean age of 27.97 ± 11.16 years at evaluation and the mean duration of treatment of 9.2 ± 6.4 years. <b> Results:</b> All four domains of WHO-QoL-BREF viz., Physical, Psychological, Social and Environmental correlated well with each other (<i> p</i> < 0.01). The NSS correlated inversely with the physical domain (<i> p</i> < 0.02), while the duration of treatment had a positive correlation with the physical domain (<i> p</i> < 0.01). None of the other features of QoL showed any significant correlation with age, NSS or duration of treatment. <b> Conclusion:</b> QoL is complementary to formal neurological assessment and should be routinely incorporated in the evaluation of outcome of patients with WD and other chronic neurological disorders.http://www.annalsofian.org/article.asp?issn=0972-2327;year=2008;volume=11;issue=1;spage=37;epage=40;aulast=KomalQuality of lifeWHO-BREFWilson′s disease |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Komal Kumar R Taly A Nair K.P.S Sinha S Prashanth L Vidya N Arunodaya G Rao S |
spellingShingle |
Komal Kumar R Taly A Nair K.P.S Sinha S Prashanth L Vidya N Arunodaya G Rao S Quality of life in <i>Wilson′s disease</i> Annals of Indian Academy of Neurology Quality of life WHO-BREF Wilson′s disease |
author_facet |
Komal Kumar R Taly A Nair K.P.S Sinha S Prashanth L Vidya N Arunodaya G Rao S |
author_sort |
Komal Kumar R |
title |
Quality of life in <i>Wilson′s disease</i> |
title_short |
Quality of life in <i>Wilson′s disease</i> |
title_full |
Quality of life in <i>Wilson′s disease</i> |
title_fullStr |
Quality of life in <i>Wilson′s disease</i> |
title_full_unstemmed |
Quality of life in <i>Wilson′s disease</i> |
title_sort |
quality of life in <i>wilson′s disease</i> |
publisher |
Wolters Kluwer Medknow Publications |
series |
Annals of Indian Academy of Neurology |
issn |
0972-2327 1998-3549 |
publishDate |
2008-01-01 |
description |
<b>Background:</b> Assessment of Quality of life (QoL) is fast assuming significance as the measure of health in many disorders. <b> Aim:</b> To correlate clinical severity and QoL in patients with Wilson′s disease (WD). <b> Materials and Methods:</b> We evaluated patients of WD on regular follow up for at least two years and aged over 18 years using Neurological Symptom Score (NSS) for clinical severity and WHO-BREF for QoL at a university teaching hospital. Patients with inability to respond to the questionnaire due to behavioral problems, low IQ or other disease related factors were excluded. These 30 patients (M:F:: 23:7) had a mean age of 27.97 ± 11.16 years at evaluation and the mean duration of treatment of 9.2 ± 6.4 years. <b> Results:</b> All four domains of WHO-QoL-BREF viz., Physical, Psychological, Social and Environmental correlated well with each other (<i> p</i> < 0.01). The NSS correlated inversely with the physical domain (<i> p</i> < 0.02), while the duration of treatment had a positive correlation with the physical domain (<i> p</i> < 0.01). None of the other features of QoL showed any significant correlation with age, NSS or duration of treatment. <b> Conclusion:</b> QoL is complementary to formal neurological assessment and should be routinely incorporated in the evaluation of outcome of patients with WD and other chronic neurological disorders. |
topic |
Quality of life WHO-BREF Wilson′s disease |
url |
http://www.annalsofian.org/article.asp?issn=0972-2327;year=2008;volume=11;issue=1;spage=37;epage=40;aulast=Komal |
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