Common germline-somatic variant interactions in advanced urothelial cancer
The role of germline variation in human cancers is not fully understood. Here, the authors define the landscape of putative deleterious germline variants that abrogate tumor suppressor proteins in advanced urothelial cancer patients.
Bibliographic Details
| Main Authors: |
Aram Vosoughi,
Tuo Zhang,
Kyrillus S. Shohdy,
Panagiotis J. Vlachostergios,
David C. Wilkes,
Bhavneet Bhinder,
Scott T. Tagawa,
David M. Nanus,
Ana M. Molina,
Himisha Beltran,
Cora N. Sternberg,
Samaneh Motanagh,
Brian D. Robinson,
Jenny Xiang,
Xiao Fan,
Wendy K. Chung,
Mark A. Rubin,
Olivier Elemento,
Andrea Sboner,
Juan Miguel Mosquera,
Bishoy M. Faltas |
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| Format: | Article
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| Language: | English |
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| Published: |
Nature Publishing Group
2020-12-01
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| Series: | Nature Communications
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| Online Access: | https://doi.org/10.1038/s41467-020-19971-8
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