Current state and future prospects of direct-to-consumer (DTC) pharmacogenetics
Direct-to-consumer (DTC) DNA testing has grown from contentious beginnings into a global industry, by providing a wide range of personal genomic information directly to its clients. These companies, typified by the well-established 23andMe, generally carry out a gene-chip analysis of single nucleoti...
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doaj-8421ebe56dd845638c1a3e05710ebba72020-11-24T22:56:52ZengFrontiers Media S.A.Frontiers in Pharmacology1663-98122012-08-01310.3389/fphar.2012.0015231126Current state and future prospects of direct-to-consumer (DTC) pharmacogeneticsEng Wee eChua0Eng Wee eChua1Martin A Kennedy2University of Otago, ChristchurchUniversiti Kebangsaan MalaysiaUniversity of Otago, ChristchurchDirect-to-consumer (DTC) DNA testing has grown from contentious beginnings into a global industry, by providing a wide range of personal genomic information directly to its clients. These companies, typified by the well-established 23andMe, generally carry out a gene-chip analysis of single nucleotide polymorphisms (SNPs) using DNA extracted from a saliva sample. These genetic data are then assimilated and provided direct to the client, with varying degrees of interpretation. Although much debate has focused on the limitations and ethical aspects of providing genotypes for disease risk alleles, the provision of pharmacogenetic results by DTC companies is less studied. We set out to evaluate current DTC pharmacogenetics offerings, and then to consider how these services might best evolve and adapt in order to play a potentially useful future role in delivery of personalized medicine.http://journal.frontiersin.org/Journal/10.3389/fphar.2012.00152/fullGenetic TestingPharmacogeneticspharmacogenomicspersonalized medicinedirect-to-consumer (DTC)personal genome |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Eng Wee eChua Eng Wee eChua Martin A Kennedy |
spellingShingle |
Eng Wee eChua Eng Wee eChua Martin A Kennedy Current state and future prospects of direct-to-consumer (DTC) pharmacogenetics Frontiers in Pharmacology Genetic Testing Pharmacogenetics pharmacogenomics personalized medicine direct-to-consumer (DTC) personal genome |
author_facet |
Eng Wee eChua Eng Wee eChua Martin A Kennedy |
author_sort |
Eng Wee eChua |
title |
Current state and future prospects of direct-to-consumer (DTC) pharmacogenetics |
title_short |
Current state and future prospects of direct-to-consumer (DTC) pharmacogenetics |
title_full |
Current state and future prospects of direct-to-consumer (DTC) pharmacogenetics |
title_fullStr |
Current state and future prospects of direct-to-consumer (DTC) pharmacogenetics |
title_full_unstemmed |
Current state and future prospects of direct-to-consumer (DTC) pharmacogenetics |
title_sort |
current state and future prospects of direct-to-consumer (dtc) pharmacogenetics |
publisher |
Frontiers Media S.A. |
series |
Frontiers in Pharmacology |
issn |
1663-9812 |
publishDate |
2012-08-01 |
description |
Direct-to-consumer (DTC) DNA testing has grown from contentious beginnings into a global industry, by providing a wide range of personal genomic information directly to its clients. These companies, typified by the well-established 23andMe, generally carry out a gene-chip analysis of single nucleotide polymorphisms (SNPs) using DNA extracted from a saliva sample. These genetic data are then assimilated and provided direct to the client, with varying degrees of interpretation. Although much debate has focused on the limitations and ethical aspects of providing genotypes for disease risk alleles, the provision of pharmacogenetic results by DTC companies is less studied. We set out to evaluate current DTC pharmacogenetics offerings, and then to consider how these services might best evolve and adapt in order to play a potentially useful future role in delivery of personalized medicine. |
topic |
Genetic Testing Pharmacogenetics pharmacogenomics personalized medicine direct-to-consumer (DTC) personal genome |
url |
http://journal.frontiersin.org/Journal/10.3389/fphar.2012.00152/full |
work_keys_str_mv |
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