TACC3–ch-TOG track the growing tips of microtubules independently of clathrin and Aurora-A phosphorylation

TACC3–ch-TOG track the growing tips of microtubules independently of clathrin and Aurora-A phosphorylation

The interaction between TACC3 (transforming acidic coiled coil protein 3) and the microtubule polymerase ch-TOG (colonic, hepatic tumor overexpressed gene) is evolutionarily conserved. Loading of TACC3–ch-TOG onto mitotic spindle microtubules requires the phosphorylation of TACC3 by Aurora-A kinase...

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Bibliographic Details
Main Authors: Cristina Gutiérrez-Caballero, Selena G. Burgess, Richard Bayliss, Stephen J. Royle
Format: Article
Language:English
Published: The Company of Biologists 2015-01-01
Series:Biology Open
Subjects:
TACC3
+TIP
ch-TOG
XMAP215
Microtubule dynamics
Online Access:http://bio.biologists.org/content/4/2/170

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