Novel Polycondensed Partly Saturated β-Carbolines Including Ferrocene Derivatives: Synthesis, DFT-Supported Structural Analysis, Mechanism of Some Diastereoselective Transformations and a Preliminary Study of their In Vitro Antiproliferative Effects

Novel Polycondensed Partly Saturated β-Carbolines Including Ferrocene Derivatives: Synthesis, DFT-Supported Structural Analysis, Mechanism of Some Diastereoselective Transformations and a Preliminary Study of their In Vitro Antiproliferative Effects

Use of a Pictet-Spengler reaction of tryptamine and <span style="font-variant: small-caps;">l</span>-tryptophan methyl ester and subsequent reduction of the nitro group followed by further cyclocondensation with aryl aldehydes and formyl–substituted carboxylic acids, including...

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Bibliographic Details
Main Authors: Kinga Judit Fodor, Dániel Hutai, Tamás Jernei, Angéla Takács, Zsófia Szász, Máté Sulyok-Eiler, Veronika Harmat, Rita Oláh Szabó, Gitta Schlosser, Ferenc Hudecz, László Kőhidai, Antal Csámpai
Format: Article
Language:English
Published: MDPI AG 2020-03-01
Series:Molecules
Subjects:
β-carboline
diastereoselectivity
conformation
ferrocene
organic synthesis
NMR spectroscopy
Online Access:https://www.mdpi.com/1420-3049/25/7/1599

Internet

https://www.mdpi.com/1420-3049/25/7/1599

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