SARS-CoV-2 Infection Causes Relapse of Kleine-Levin Syndrome: Case Report and Review of Literature

Recurrent episodes of hypersomnia, hypersexuality, compulsive eating, behavioral and cognitive disturbances, are the basic clinical features of Kleine-Levin syndrome (KLS). Our case report describes a patient who was diagnosed with KLS at the age of 20. With appropriate therapy, the disease had a sa...

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Main Authors: Marino Marčić, Ljiljana Marčić, Barbara Marčić
Format: Article
Language:English
Published: MDPI AG 2021-07-01
Series:Neurology International
Subjects:
Online Access:https://www.mdpi.com/2035-8377/13/3/33
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spelling doaj-845a017818d240f08dfadb39ea7291c52021-09-26T00:50:02ZengMDPI AGNeurology International2035-83772021-07-01133332833410.3390/neurolint13030033SARS-CoV-2 Infection Causes Relapse of Kleine-Levin Syndrome: Case Report and Review of LiteratureMarino Marčić0Ljiljana Marčić1Barbara Marčić2Department of Neurology, University Hospital Center Split, Spinčićeva1, 21000 Split, CroatiaDepartment of Radiology, Polyclinic Medikol, 21000 Split, CroatiaDepartment of Histology, School of Medicine, University of Mostar, 88000 Mostar, Bosnia and HerzegovinaRecurrent episodes of hypersomnia, hypersexuality, compulsive eating, behavioral and cognitive disturbances, are the basic clinical features of Kleine-Levin syndrome (KLS). Our case report describes a patient who was diagnosed with KLS at the age of 20. With appropriate therapy, the disease had a satisfactory course until patient had a moderate form of SARS-CoV-2 infection, which led to a significant exacerbation of all symptoms. SARS-CoV-2 virus can cause almost any neurological disease, and relapse of KLS is another evidence of neurotropicity of the virus.https://www.mdpi.com/2035-8377/13/3/33SARS-CoV-2Kleine-Levinhypersomniahyperphagia
collection DOAJ
language English
format Article
sources DOAJ
author Marino Marčić
Ljiljana Marčić
Barbara Marčić
spellingShingle Marino Marčić
Ljiljana Marčić
Barbara Marčić
SARS-CoV-2 Infection Causes Relapse of Kleine-Levin Syndrome: Case Report and Review of Literature
Neurology International
SARS-CoV-2
Kleine-Levin
hypersomnia
hyperphagia
author_facet Marino Marčić
Ljiljana Marčić
Barbara Marčić
author_sort Marino Marčić
title SARS-CoV-2 Infection Causes Relapse of Kleine-Levin Syndrome: Case Report and Review of Literature
title_short SARS-CoV-2 Infection Causes Relapse of Kleine-Levin Syndrome: Case Report and Review of Literature
title_full SARS-CoV-2 Infection Causes Relapse of Kleine-Levin Syndrome: Case Report and Review of Literature
title_fullStr SARS-CoV-2 Infection Causes Relapse of Kleine-Levin Syndrome: Case Report and Review of Literature
title_full_unstemmed SARS-CoV-2 Infection Causes Relapse of Kleine-Levin Syndrome: Case Report and Review of Literature
title_sort sars-cov-2 infection causes relapse of kleine-levin syndrome: case report and review of literature
publisher MDPI AG
series Neurology International
issn 2035-8377
publishDate 2021-07-01
description Recurrent episodes of hypersomnia, hypersexuality, compulsive eating, behavioral and cognitive disturbances, are the basic clinical features of Kleine-Levin syndrome (KLS). Our case report describes a patient who was diagnosed with KLS at the age of 20. With appropriate therapy, the disease had a satisfactory course until patient had a moderate form of SARS-CoV-2 infection, which led to a significant exacerbation of all symptoms. SARS-CoV-2 virus can cause almost any neurological disease, and relapse of KLS is another evidence of neurotropicity of the virus.
topic SARS-CoV-2
Kleine-Levin
hypersomnia
hyperphagia
url https://www.mdpi.com/2035-8377/13/3/33
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