Ovariectomy-Induced Hepatic Lipid and Cytochrome P450 Dysmetabolism Precedes Serum Dyslipidemia

Ovariectomy-Induced Hepatic Lipid and Cytochrome P450 Dysmetabolism Precedes Serum Dyslipidemia

Ovarian hormone deficiency leads to increased body weight, visceral adiposity, fatty liver and disorders associated with menopausal metabolic syndrome. To better understand the underlying mechanisms of these disorders in their early phases of development, we investigated the effect of ovariectomy on...

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Bibliographic Details
Main Authors: Hana Malinská, Martina Hüttl, Denisa Miklánková, Jaroslava Trnovská, Iveta Zapletalová, Martin Poruba, Irena Marková
Format: Article
Language:English
Published: MDPI AG 2021-04-01
Series:International Journal of Molecular Sciences
Subjects:
ovariectomy
metabolic syndrome
brown adipose tissue
hepatic steatosis
obesity
insulin resistance
Online Access:https://www.mdpi.com/1422-0067/22/9/4527

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