Optimized photochemistry enables efficient analysis of dynamic RNA structuromes and interactomes in genetic and infectious diseases
RNA crosslinking and proximity ligation methods are used to identify transcriptome-wide base pairing interactions. Here, the authors report PARIS2 (psoralen analysis of RNA interactions and structures 2), a method for RNA duplex determination in vivo with higher efficiency than the previous PARIS me...
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| Format: | Article |
| Language: | English |
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Nature Publishing Group
2021-04-01
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| Series: | Nature Communications |
| Online Access: | https://doi.org/10.1038/s41467-021-22552-y |
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doaj-84b70984cb2f4a888c00803699c67bcd2021-04-25T11:13:50ZengNature Publishing GroupNature Communications2041-17232021-04-0112111410.1038/s41467-021-22552-yOptimized photochemistry enables efficient analysis of dynamic RNA structuromes and interactomes in genetic and infectious diseasesMinjie Zhang0Kongpan Li1Jianhui Bai2Willem A. Velema3Chengqing Yu4Ryan van Damme5Wilson H. Lee6Maia L. Corpuz7Jian-Fu Chen8Zhipeng Lu9Department of Pharmacology and Pharmaceutical Sciences, School of Pharmacy, University of Southern CaliforniaDepartment of Pharmacology and Pharmaceutical Sciences, School of Pharmacy, University of Southern CaliforniaDepartment of Pharmacology and Pharmaceutical Sciences, School of Pharmacy, University of Southern CaliforniaInstitute for Molecules and Materials, Radboud University NijmegenDepartment of Pharmacology and Pharmaceutical Sciences, School of Pharmacy, University of Southern CaliforniaDepartment of Pharmacology and Pharmaceutical Sciences, School of Pharmacy, University of Southern CaliforniaDepartment of Pharmacology and Pharmaceutical Sciences, School of Pharmacy, University of Southern CaliforniaDepartment of Pharmacology and Pharmaceutical Sciences, School of Pharmacy, University of Southern CaliforniaCenter for Craniofacial Molecular Biology, University of Southern CaliforniaDepartment of Pharmacology and Pharmaceutical Sciences, School of Pharmacy, University of Southern CaliforniaRNA crosslinking and proximity ligation methods are used to identify transcriptome-wide base pairing interactions. Here, the authors report PARIS2 (psoralen analysis of RNA interactions and structures 2), a method for RNA duplex determination in vivo with higher efficiency than the previous PARIS method.https://doi.org/10.1038/s41467-021-22552-y |
| collection |
DOAJ |
| language |
English |
| format |
Article |
| sources |
DOAJ |
| author |
Minjie Zhang Kongpan Li Jianhui Bai Willem A. Velema Chengqing Yu Ryan van Damme Wilson H. Lee Maia L. Corpuz Jian-Fu Chen Zhipeng Lu |
| spellingShingle |
Minjie Zhang Kongpan Li Jianhui Bai Willem A. Velema Chengqing Yu Ryan van Damme Wilson H. Lee Maia L. Corpuz Jian-Fu Chen Zhipeng Lu Optimized photochemistry enables efficient analysis of dynamic RNA structuromes and interactomes in genetic and infectious diseases Nature Communications |
| author_facet |
Minjie Zhang Kongpan Li Jianhui Bai Willem A. Velema Chengqing Yu Ryan van Damme Wilson H. Lee Maia L. Corpuz Jian-Fu Chen Zhipeng Lu |
| author_sort |
Minjie Zhang |
| title |
Optimized photochemistry enables efficient analysis of dynamic RNA structuromes and interactomes in genetic and infectious diseases |
| title_short |
Optimized photochemistry enables efficient analysis of dynamic RNA structuromes and interactomes in genetic and infectious diseases |
| title_full |
Optimized photochemistry enables efficient analysis of dynamic RNA structuromes and interactomes in genetic and infectious diseases |
| title_fullStr |
Optimized photochemistry enables efficient analysis of dynamic RNA structuromes and interactomes in genetic and infectious diseases |
| title_full_unstemmed |
Optimized photochemistry enables efficient analysis of dynamic RNA structuromes and interactomes in genetic and infectious diseases |
| title_sort |
optimized photochemistry enables efficient analysis of dynamic rna structuromes and interactomes in genetic and infectious diseases |
| publisher |
Nature Publishing Group |
| series |
Nature Communications |
| issn |
2041-1723 |
| publishDate |
2021-04-01 |
| description |
RNA crosslinking and proximity ligation methods are used to identify transcriptome-wide base pairing interactions. Here, the authors report PARIS2 (psoralen analysis of RNA interactions and structures 2), a method for RNA duplex determination in vivo with higher efficiency than the previous PARIS method. |
| url |
https://doi.org/10.1038/s41467-021-22552-y |
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