Bacteriological Spectrum and Antimicrobial Resistance Pattern in A Multidisciplinary Intensive Care Unit
Introduction: In Intensive Care Units, the rate of infection due to multidrug resistant pathogens is high and accounts for increase in duration of hospital stay, mortality and morbidity and cost incurred to the patient as well as the hospital. The pathogens responsible for infection vary greatly...
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doaj-84bf22c378ed4b14987a4267ecced0702020-11-25T02:47:48ZengJCDR Research and Publications Pvt. Ltd.National Journal of Laboratory Medicine2277-85512455-68822015-10-0144283210.7860/NJLM/2015/13980:2076Bacteriological Spectrum and Antimicrobial Resistance Pattern in A Multidisciplinary Intensive Care UnitSudhamani0Anushka Vaijnath Devnikar1Sagar Hanamant Mali2Beena Madappa Parvangada3Post Graduate, Department of Microbiology, Sri Devaraj Urs Medical College, Tamaka, Kolar, India.Lecturer, Department of Microbiology, Sri Devaraj Urs Medical College, Tamaka, Kolar, India.Post Graduate, Department of Microbiology, Sri Devaraj Urs Medical College, Tamaka, Kolar, India.Professor and HOD, Department of Microbiology, Sri Devaraj Urs Medical College, Tamaka, Kolar, India.Introduction: In Intensive Care Units, the rate of infection due to multidrug resistant pathogens is high and accounts for increase in duration of hospital stay, mortality and morbidity and cost incurred to the patient as well as the hospital. The pathogens responsible for infection vary greatly from place to place. Aim: To identify the spectrum of bacterial pathogens and their anti-microbial resistance pattern in a multi-disciplinary Intensive Care Unit (ICU). Materials and Methods: A retrospective study was conducted in the Department of Microbiology from May 2013 – April 2014. All clinical samples received in the microbiology lab from the intensive care unit which were positive by culture were included in this study. They were processed according to standard microbiological methods. Antimicrobial susceptibility testing was done by Kirby Bauer’s disc diffusion method and the results were interpreted according to Clinical Laboratory Standards Institute (CLSI) guidelines. Detection of Methicillin Resistant Staphylococcus aureus (MRSA) and Extended Spectrum Beta Lactamase (ESBL) was also done as per CLSI guidelines. Results: A total of 186 samples were processed. The most frequent isolate was Acinetobacter species (21%). Endotracheal (ET) aspirate (45.2%) was the most common source for these isolates. Methicillin resistance was detected in 25% of the Staphylococcus isolates. Of the 88 Enterobacteriaceae isolates, 30% were found to be Extended Spectrum β-Lactamase (ESBL) producers. Klebsiella species accounted for 40.5% of the ESBL producers. The resistance rates to antimicrobials were higher for Acinetobacter species including 41% resistance to imipenem. Conclusion: Acinetobacter species was the most frequently isolated organism which showed higher resistance pattern. Multidrug resistant organisms are on the rise and strict measures are required to control infections due to these organisms.http://www.njlm.net/articles/PDF/2076/7-%2013980_F(Sh)_PF1(VSUAK)_PFA(AK)_PF2(PAG).pdfantimicrobial susceptibilityicu infectionsmultidrug resistance |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Sudhamani Anushka Vaijnath Devnikar Sagar Hanamant Mali Beena Madappa Parvangada |
spellingShingle |
Sudhamani Anushka Vaijnath Devnikar Sagar Hanamant Mali Beena Madappa Parvangada Bacteriological Spectrum and Antimicrobial Resistance Pattern in A Multidisciplinary Intensive Care Unit National Journal of Laboratory Medicine antimicrobial susceptibility icu infections multidrug resistance |
author_facet |
Sudhamani Anushka Vaijnath Devnikar Sagar Hanamant Mali Beena Madappa Parvangada |
author_sort |
Sudhamani |
title |
Bacteriological Spectrum and Antimicrobial Resistance Pattern in A Multidisciplinary Intensive Care Unit |
title_short |
Bacteriological Spectrum and Antimicrobial Resistance Pattern in A Multidisciplinary Intensive Care Unit |
title_full |
Bacteriological Spectrum and Antimicrobial Resistance Pattern in A Multidisciplinary Intensive Care Unit |
title_fullStr |
Bacteriological Spectrum and Antimicrobial Resistance Pattern in A Multidisciplinary Intensive Care Unit |
title_full_unstemmed |
Bacteriological Spectrum and Antimicrobial Resistance Pattern in A Multidisciplinary Intensive Care Unit |
title_sort |
bacteriological spectrum and antimicrobial resistance pattern in a multidisciplinary intensive care unit |
publisher |
JCDR Research and Publications Pvt. Ltd. |
series |
National Journal of Laboratory Medicine |
issn |
2277-8551 2455-6882 |
publishDate |
2015-10-01 |
description |
Introduction: In Intensive Care Units, the rate of infection
due to multidrug resistant pathogens is high and accounts for
increase in duration of hospital stay, mortality and morbidity
and cost incurred to the patient as well as the hospital. The
pathogens responsible for infection vary greatly from place to
place.
Aim: To identify the spectrum of bacterial pathogens and
their anti-microbial resistance pattern in a multi-disciplinary
Intensive Care Unit (ICU).
Materials and Methods: A retrospective study was conducted
in the Department of Microbiology from May 2013 – April 2014.
All clinical samples received in the microbiology lab from the
intensive care unit which were positive by culture were included
in this study. They were processed according to standard
microbiological methods. Antimicrobial susceptibility testing
was done by Kirby Bauer’s disc diffusion method and the results
were interpreted according to Clinical Laboratory Standards
Institute (CLSI) guidelines. Detection of Methicillin Resistant
Staphylococcus aureus (MRSA) and Extended Spectrum Beta
Lactamase (ESBL) was also done as per CLSI guidelines.
Results: A total of 186 samples were processed. The most
frequent isolate was Acinetobacter species (21%). Endotracheal (ET) aspirate (45.2%) was the most common source for
these isolates. Methicillin resistance was detected in 25% of the
Staphylococcus isolates. Of the 88 Enterobacteriaceae isolates,
30% were found to be Extended Spectrum β-Lactamase
(ESBL) producers. Klebsiella species accounted for 40.5% of
the ESBL producers. The resistance rates to antimicrobials
were higher for Acinetobacter species including 41% resistance
to imipenem.
Conclusion: Acinetobacter species was the most frequently
isolated organism which showed higher resistance pattern.
Multidrug resistant organisms are on the rise and strict measures
are required to control infections due to these organisms. |
topic |
antimicrobial susceptibility icu infections multidrug resistance |
url |
http://www.njlm.net/articles/PDF/2076/7-%2013980_F(Sh)_PF1(VSUAK)_PFA(AK)_PF2(PAG).pdf |
work_keys_str_mv |
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