Evaluation of genetic markers as instruments for Mendelian randomization studies on vitamin D.

Evaluation of genetic markers as instruments for Mendelian randomization studies on vitamin D.

BACKGROUND:Mendelian randomization (MR) studies use genetic variants mimicking the influence of a modifiable exposure to assess and quantify a causal association with an outcome, with an aim to avoid problems with confounding and reverse causality affecting other types of observational studies. AIM:...

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Bibliographic Details
Main Authors: Diane J Berry, Karani S Vimaleswaran, John C Whittaker, Aroon D Hingorani, Elina Hyppönen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3357436?pdf=render

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