Oxymatrine Attenuates Tumor Growth and Deactivates STAT5 Signaling in a Lung Cancer Xenograft Model

Oxymatrine Attenuates Tumor Growth and Deactivates STAT5 Signaling in a Lung Cancer Xenograft Model

Oxymatrine (OMT) is a major alkaloid found in radix Sophorae flavescentis extract and has been reported to exhibit various pharmacological activities. We elucidated the detailed molecular mechanism(s) underlying the therapeutic actions of OMT in non-small cell lung cancer (NSCLC) cells and a xenogra...

Full description

Bibliographic Details
Main Authors: Young Yun Jung, Muthu K. Shanmugam, Acharan S. Narula, Chulwon Kim, Jong Hyun Lee, Ojas A. Namjoshi, Bruce E. Blough, Gautam Sethi, Kwang Seok Ahn
Format: Article
Language:English
Published: MDPI AG 2019-01-01
Series:Cancers
Subjects:
oxymatrine
STAT5
apoptosis
NSCLC
Online Access:http://www.mdpi.com/2072-6694/11/1/49

Internet

http://www.mdpi.com/2072-6694/11/1/49

Similar Items