Cellular senescence in the aging retina and developments of senotherapies for age-related macular degeneration
Abstract Age-related macular degeneration (AMD), a degenerative disease in the central macula area of the neuroretina and the supporting retinal pigment epithelium, is the most common cause of vision loss in the elderly. Although advances have been made, treatment to prevent the progressive degenera...
Main Authors: | Keng Siang Lee, Shuxiao Lin, David A. Copland, Andrew D. Dick, Jian Liu |
---|---|
Format: | Article |
Language: | English |
Published: |
BMC
2021-01-01
|
Series: | Journal of Neuroinflammation |
Subjects: | |
Online Access: | https://doi.org/10.1186/s12974-021-02088-0 |
Similar Items
-
Cytoprotective Potential of Fucoxanthin in Oxidative Stress-Induced Age-Related Macular Degeneration and Retinal Pigment Epithelial Cell Senescence In Vivo and In Vitro
by: Shiu-Jau Chen, et al.
Published: (2021-02-01) -
Molecular Mechanisms of Druze Formation in the Retina in Age-Related Macular Degeneration
by: E. F. Barinov
Published: (2020-11-01) -
Comparison of histologic findings in age-related macular degeneration with RPE flatmount images
by: Qing Zhang, et al.
Published: (2019-02-01) -
Disruptions of Autophagy in the Rat Retina with Age During the Development of Age-Related-Macular-Degeneration-like Retinopathy
by: Oyuna S. Kozhevnikova, et al.
Published: (2019-09-01) -
Review of graft rejection in age-related macular degeneration replacement therapy
by: Xi-Ying Mao, et al.
Published: (2016-02-01)