Adult Celiac Disease: The Importance of Extraintestinal Manifestations
Celiac disease (CD) is a chronic immune-mediated enteropathy driven by gluten and affecting individuals of all ages. The diagnosis of CD in adulthood is emerging and patients often present with nonclassical extraintestinal manifestations. We report the case of a 53-year-old man presenting with neuro...
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doaj-84f277af68384cd7b1ae223c8dd8227f2020-11-25T02:32:47ZengKarger PublishersGE: Portuguese Journal of Gastroenterology2341-45452387-19542017-03-0110.1159/000461593461593Adult Celiac Disease: The Importance of Extraintestinal ManifestationsGonçalo NunesRita BarosaMarta PatitaVítor FernandesDiogo GonçalvesJorge FonsecaCeliac disease (CD) is a chronic immune-mediated enteropathy driven by gluten and affecting individuals of all ages. The diagnosis of CD in adulthood is emerging and patients often present with nonclassical extraintestinal manifestations. We report the case of a 53-year-old man presenting with neuromuscular symptoms, skin rash, inconspicuous chronic diarrhea, marked weight loss, and biochemical markers of malabsorption. A strong clinical suspicion led to the diagnosis of CD with clinical recovery after the initiation of a gluten-free diet. Clinical presentation with atypical symptoms in adult CD patients is the rule and not the exception. Most of the extraintestinal manifestations depend on background autoimmune phenomena and micronutrient malabsorption. A gluten-free diet re-establishes homeostasis and prevents long-term complications.http://www.karger.com/Article/FullText/461593GlutenExtraintestinal manifestationsCeliac disease |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Gonçalo Nunes Rita Barosa Marta Patita Vítor Fernandes Diogo Gonçalves Jorge Fonseca |
spellingShingle |
Gonçalo Nunes Rita Barosa Marta Patita Vítor Fernandes Diogo Gonçalves Jorge Fonseca Adult Celiac Disease: The Importance of Extraintestinal Manifestations GE: Portuguese Journal of Gastroenterology Gluten Extraintestinal manifestations Celiac disease |
author_facet |
Gonçalo Nunes Rita Barosa Marta Patita Vítor Fernandes Diogo Gonçalves Jorge Fonseca |
author_sort |
Gonçalo Nunes |
title |
Adult Celiac Disease: The Importance of Extraintestinal Manifestations |
title_short |
Adult Celiac Disease: The Importance of Extraintestinal Manifestations |
title_full |
Adult Celiac Disease: The Importance of Extraintestinal Manifestations |
title_fullStr |
Adult Celiac Disease: The Importance of Extraintestinal Manifestations |
title_full_unstemmed |
Adult Celiac Disease: The Importance of Extraintestinal Manifestations |
title_sort |
adult celiac disease: the importance of extraintestinal manifestations |
publisher |
Karger Publishers |
series |
GE: Portuguese Journal of Gastroenterology |
issn |
2341-4545 2387-1954 |
publishDate |
2017-03-01 |
description |
Celiac disease (CD) is a chronic immune-mediated enteropathy driven by gluten and affecting individuals of all ages. The diagnosis of CD in adulthood is emerging and patients often present with nonclassical extraintestinal manifestations. We report the case of a 53-year-old man presenting with neuromuscular symptoms, skin rash, inconspicuous chronic diarrhea, marked weight loss, and biochemical markers of malabsorption. A strong clinical suspicion led to the diagnosis of CD with clinical recovery after the initiation of a gluten-free diet. Clinical presentation with atypical symptoms in adult CD patients is the rule and not the exception. Most of the extraintestinal manifestations depend on background autoimmune phenomena and micronutrient malabsorption. A gluten-free diet re-establishes homeostasis and prevents long-term complications. |
topic |
Gluten Extraintestinal manifestations Celiac disease |
url |
http://www.karger.com/Article/FullText/461593 |
work_keys_str_mv |
AT goncalonunes adultceliacdiseasetheimportanceofextraintestinalmanifestations AT ritabarosa adultceliacdiseasetheimportanceofextraintestinalmanifestations AT martapatita adultceliacdiseasetheimportanceofextraintestinalmanifestations AT vitorfernandes adultceliacdiseasetheimportanceofextraintestinalmanifestations AT diogogoncalves adultceliacdiseasetheimportanceofextraintestinalmanifestations AT jorgefonseca adultceliacdiseasetheimportanceofextraintestinalmanifestations |
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1724817787954659328 |